The objective of this study was to demonstrate that stem cells isolated from discarded skin obtained after debridement can be used with collagen and fibrin-based scaffolds to develop a tissue-engineered vascularized dermal equivalent. Discarded tissue samples were collected from severely burned patients undergoing wound debridement. Stem cells were isolated from the adipose tissue layer and the...

Objective: Debridement to remove necrotic and/or infected tissue and promote active healing remains a cornerstone of contemporary chronic wound management. While there has been a recent shift toward less invasive polymer-based debriding devices, their efficacy requires rigorous evaluation. Approach: This study was designed to directly compare monofilament debriding devices to traditional gauze ...

The occurrence of mediastinitis following synthetic vascular replacement surgery is still associated with an unfavorable prognosis in the treatment of thoracic aortic diseases. This time we report a Bentall procedure that we re-performed to treat an aortic root pseudoaneurysm, which developed after a postoperative mediastinitis. This followed the first Bentall procedure, which was treated by de...

Introduction: This study was carried out to compare two retrograde filling materials entitled mineral trioxide aggregate (MTA) and Root MTA (RMTA) in regard to their marginal adaptation and surface defects. Method: In this study twenty extracted human teeth were used. In all teeth after cleaning and shaping, the root canals were obturated by gutta-percha and root canal sealer. After that in eac...

In conventional endodontic treatment, alkaline solutions of sodium hypochlorite (NaOCl) and ethylenediaminetetraacetic acid (EDTA) are used in combination to disinfect the root canal system and to eliminate debris and smear layers. An important concept that has emerged over recent years is the use of active physical methods for agitating these fluids to improve their penetration within areas th...

Complete debridement, thorough disinfection and optimal sealing of the root canal system are the major challenges associated with endodontic treatment of teeth with open apices. In such teeth, thin radicular dentinal walls are susceptible to fracture. To ensure a better prognosis in such fractured prone thin dentinal walls, internal radicular reinforcement with various adhesive materials like g...

Pathogenic bacteria located in the subgingival area can cause periodontal diseases, gingivitis, and periodontitis. These bacterial species stick to the root surfaces and are found in a complex structure called dental plaque, which is a form of biofilm. Dental plaque, where appropriate oral hygiene is lacking, may become calcified, thereby creating calculus mainly formed from crystalline. The po...

The histopathology of active and arrested human root caries was examined in extracted teeth by different optical methods. Significant differences were observed between the mechanisms operating on the various dental structures. Three different patterns of initial cementum and dentin lesions could be distinguished, depending on the severity of the cariogenic attack, the degree of sclerosis of the...

To date, scarce evidence exists around the application of subgingival air polishing during treatment severe periodontitis. The aim this study was to evaluate benefits non-surgical deep bleeding pockets in stages III–IV periodontitis patients Forty with were selected, and probing depth (PD) 5–9 mm on (BoP) selected as experimental sites. All underwent a full-mouth session erythritol powder supra...