Portfolio risk management plays an important role in successful investments. standard deviation, value-at-risk, expected shortfall, and maximum absolute deviation are widely used portfolio measures. However, the existing measures vulnerable to larger skewness kurtosis of asset returns. Moreover, traditional assumption normality returns leads underestimation risk. Cryptocurrencies a decentralize...

BACKGROUND AND PURPOSE Stroke is emerging as a major public health problem for women, as it is for men. Controversy persists regarding gender differences in stroke incidence, severity, and poststroke disability. METHODS Participants in the Framingham Original (n=5119; 2829 women) and Offspring (n=4957, 2565 women) cohorts who were 45 years and stroke-free were followed to first incident strok...

Recently, cyber security has become an important topic on the agenda of many organisations. It is already widely acknowledged that attacks do happen, and decision makers face the problem of how to respond. As it is almost impossible to secure a complex system completely, it is important to have an adequate estimate of the effectiveness of security measures when making investment decisions. Risk...

BACKGROUND There are increasing numbers of randomised trials and systematic reviews examining the efficacy of interventions designed to bring about a change in clinical practice. The findings of this research are being used to guide strategies to increase the uptake of evidence into clinical practice. Knowledge of the outcomes measured by these trials is vital not only for the interpretation an...

Patient reported outcome measures (PROMs) are a useful way of recording patient perceptions of the impact of their cancer and the consequences of treatment. Understanding the impact of radiotherapy longer term requires tools that are sensitive to change but also meaningful for patients. PROMs are useful in defining symptom severity but also the burden of illness for cancer patients. Patient rep...

PURPOSE The US Preventive Services Task Force (USPSTF) is authorized by the US government to review and disseminate the scientific evidence for clinical preventive services. The purpose of this study was to evaluate the alignment of Medicare preventive services coverage with the recommendations of the USPSTF before implementation of health reform. METHODS We recorded all Medicare coverage for...

We describe the use of a number of outcome measures that have been used over the past eight years to evaluate adult psychological therapies services in the Wakefield & Pontefract locality of the South West Yorkshire Mental Health NHS Trust. The psychological therapies service now has a unique database of outcome measures completed by 5563 clients, which has been used nationally and internationa...

Introduction: The steel industry is known as the most important consumer of energy and fuel. In doing so, ensuring safety of energy sources of a country needs to expect the risks analysis in order to select a comprehensive approach. This study aimed to identify the energy consumption and control measures available in the Hot Rolling Kavir Steel Complex and to conduct risk assessment by Energy...