The 3VHE protein is considered as a potential target for the treatment of prostate cancer. In order to find new inhibitors, pharmacophore models based on molecular structure rhodanine derivatives and three-dimensional quantitative structure-activity relationship model (3D-QSAR) have been developed validated by different methods. 3D-QSAR was evaluated its predictive performance diverse test set ...

background and objectives: angiogenesis is essential for tumor survival. inhibiting angiogenesis could be a mechanism for hindering tumor development. numerous studies have now been focused on agiogenesis inhibitors and many of such studies have targeted plant materials. in the present study, crocus pallasii subsp. haussknechtii has been evaluated for anti-angiogenesis properties. methods: anti...

We have developed new small-molecule electron donors, SMBDT-S and SMBDT-SF, based on benzo[1,2-b:4,5-b’]dithiophene (BDT) with thiophene side chains as a core unit rhodanine end-capping units to enhance the open-circuit voltage (Voc), which is one of factors limiting performance organic photovoltaics (OPVs). The SMBDT-SF donor molecules exhibited excellent thermal stability high crystallinity. ...

a multiple colorimetric assay has been introduced to evaluate the proliferation and determination of survival fraction (sf) of irradiated cells. the estimation of sf based on the cell‑growth curve information is the major advantage of this assay. in this study, the utility of multiple‑mts assay for the sf estimation of irradiated ht‑29 colon cancer cells, which were plated before irradiation, w...