OBJECTIVES To determine if patients with rheumatoid arthritis have increased risk of atrial fibrillation and stroke. DESIGN Longitudinal nationwide register based cohort study. SETTING Inpatient and outpatient hospital care in Denmark from 1997 to 2009. PARTICIPANTS Entire Danish population aged over 15 years without rheumatoid arthritis, atrial fibrillation, or stroke before 1997. Partic...

The aim of this study was to assess the percentage of respiratory disorders and airway obstruction in patients with rheumatoid arthritis by comparing lung function test results between patients with rheumatoid arthritis and control subjects with other rheumatological conditions. A prospective case-control study of respiratory symptoms and lung function abnormalities was performed in a series of...

conclusions the risk of ra increased with delayed menarche, advanced maternal age at first delivery and early age at menopause. however, longer duration of breast-feeding, parity, large number of children and consumption of ocs were found as protective independent variables against ra. methods this case-control study was conducted on 231 patients with ra and 238 controls among females aged 26 -...

rheumatoid arthritis (ra) patients are vulnerable to cardiovascular morbidity and mortality in which atherosclerosis plays a major role. in this study, the lipid profile and fasting blood sugar (fbs) of ra patients receiving a complementary medicine of olive and fig, as add-on therapy for routine disease-modifying antirheumatic drugs (dmards) regimen containing low dose methotrexate (mtx), were...

the association of rs10818488 snp located in traf1/c5 region with rheumatoid arthritis (ra), has been picked up by genome-wide association studies. independent studies in different populations revealed inconsistent results. the aim of this study was to investigate the possible association of this snp with ra in iranian population. a total of 362 cases and 422 healthy controls were recruited in ...

introduction: the activity of hypothalamus-pituitary-adrenal (hpa) axis is increased following inflammation due to its closed relation with immune system. this axis indicates an increased secretion of acth, and corticosterone during acute inflammation while little is known about its activity during chronic inflammation such as rheumatoid arthritis (ra). in this study we measured the products of...

OBJECTIVES To validate 99mTc-labeled arginylglycylaspartic acid (99mTc-3PRGD2) scintigraphy as a means to image synovial neoangiogenesis in joints afflicted by rheumatoid arthritis and to investigate its potential in the early detection and management of rheumatoid arthritis. METHODS Rheumatoid arthritis and osteoarthritis were generated in Sprague Dawley rats by type II collagen immunization...

Background: Rheumatoid arthritis is the most prevalent chronic rheumatologic disease of children. The quality of life (QOL) in these individuals is affected by physical pain, discomfort, treatment complications, and frequent absences from school leading to academic failure. No research similar to the present investigation was performed in this area. Aim: ...

Background: There is no clear consensus regarding the potential of denosumab for increasing the risk of infection in patients who concurrently receive biologic disease-modifying anti-rheumatic drugs (bDMARDs). In this study, we compared the rate of infection in postmenopausal women with rheumatoid arthritis who received concurrent bDMARDs and denosumab with those who received bDMARDs alone.   ...

Methotrexate nodulosis in conditions other than rheumatoid arthritis is very rare. It has been reported in a patient with systemic lupus erythematosus and Jaccoud’s arthropathy [4], a patient with juvenile arthritis who was rheumatoid factor negative [5], and a patient with psoriatic arthritis and negative rheumatoid factor [6]. Only the patient with juvenile arthritis had pulmonary nodules. Ho...