Rhabdomyolysis, the disintegration of skeletal muscle, is a common cause of acute renal failure. This clinical entity occurs mainly from 2 sources: traumatic and nontraumatic. Traumatic rhabdomyolysis has been described as crush syndrome during war and natural disasters. In modern or peace time, the majority of cases of rhabdomyolysis are nontraumatic, and alcohol abuse is one of the most commo...

Viral infections have been associated with a wide spectrum of muscle disorders, ranging from acute nonspecific myalgia to myositis. However, severe rhabdomyolysis, with or without accompanying acute renal failure (ARF), has been described only rarely. We report the fourth case in the literature of recent Coxsackie B virus infection complicated by severe rhabdomyolysis and ARF, necessitating tem...

Mild elevation of creatine kinase (CK) is common in untreated hypothyroidism, but severe myositis and overt rhabdomyolysis are rare. Similarly, muscle pain and CK elevation are potential side effects of statin therapy, yet rhabdomyolysis is likewise rare in the absence of medication interactions adversely affecting statin metabolism. The coexistence of statin therapy and hypothyroid states may ...

Rhabdomyolysis is a well-documented side effect of statin therapy. This risk is increased with concurrent use of medications that inhibit cytochrome p450-3A4 (CYP3A4), such as macrolide antibiotics. We present the case of a 67-year-old patient who was commenced on clarithromycin on a background of simvastatin therapy, resulting in rhabdomyolysis. This case highlights the need for awareness of c...

Ibuprofen is widely used in the community to manage pain, inflammation and fever. In cases of prolonged and supratherapeutic ingestion of ibuprofen, renal tubular acidosis (RTA) with profound hypokalemia may occur. Although hypokalemia is known to cause rhabdomyolysis, rhabdomyolysis occurring in the setting of ibuprofen-induced RTA is rare. We present an unusual case of a 34-year-old male who ...

Rhabdomyolysis is a life-threatening syndrome caused by skeletal muscle injury, which results in the leakage of myoglobin, other intracellular proteins and electrolytes into the circulatory system and urine. Acute kidney injury occurs in 13-50% of patients with rhabdomyolysis, which is the principal cause of their mortality. This is to report an emergency operation performed on a patient with t...

Hyperglycemic hyperosmolar nonketotic syndrome (HHNS) is one of the most severe acute complications of diabetes. The hallmark of HHNS is profound dehydration, marked hyperglycemia, and often some degree of neurologic impairment with mild or no ketosis [1]. Rhabdomyolysis is an unusual but underestimated complication of HHNS [2]. HHNS accompanied with rhabdomyolysis in diabetic patients was repo...

Rhabdomyolysis is a rare but potentially lethal clinical syndrome that results from acute muscle fiber necrosis with leakage of muscle constituents into blood. This devastating disease could be due to muscle compression caused by urologic positioning for a lengthy nephrectomy. In this regard, laparoscopic renal surgery may be a risk for the development of rhabdomyolysis. This phenomenon of mass...

We report a 9-year-old Japanese girl who presented with muscle weakness and elevated serum levels of muscle-derived enzymes following mycoplasma infection. Rhabdomyolysis or myositis was suggested by magnetic resonance imaging and repeated four times within 4 years. Each episode developed following respiratory infection and spontaneously recovered. The diagnosis of Sjögren’s syndrome was made b...

Rhabdomyolysis is a rare complication that emerges in a variety of infectious diseases, such as tsutsugamushi infection. In this study, we report a 71-year-old female patient with tsutsugamushi infection who exhibiting rhabdomyolysis and acute renal failure. On admission, an eschar, which is characteristic of tsutsugamushi infection, was found on her right flank area. Moreover, her tsutsugamush...