A dodecylphosphocholine micelle of 86 monomers with 5776 water molecules has been simulated under NPT conditions for 3.2 ns using GROMACS2.0. The micelle was found to be very dynamic. Some of the C-C bonds, independent of their position in the DPC monomer, adopt gauche conformation and the trans <--> gauche transitions are quite frequent. An average of about 11% of the C-C bonds in the micelle ...

The surfactants cesium, tetramethylammonium, tetraethylammonium, tetrapropylammonium and tetrabutylammonium dodecyl sulfates (CsDS, TMADS, TEADS, TPADS, and TBADS) have been synthesized by ion-exchange. The critical micellization concentration in the absence of added salt (cmc) has been determined at 10, 25, and 40 °C using the electrical conductivity method. The cmc was found to decrease in th...

To investigate the importance of the physical state of phospholipids for activation of protein kinase C, we have used short chain phospholipids, which, depending on their concentration, can exist as either monomers or micelles. We previously reported that short chain phosphatidylcholines (PC) can activate protein kinase C at concentrations that correlate with the critical micelle concentration ...

This thesis describes the synthesis of yttrium oxide nanoparticles in an AOT/isooctane reverse micelle solution. Two synthetic methods are compared. First is the precipitation reaction between yttrium nitrate and ammonia, second is the hydrolysis of yttrium isopropoxide. The effects of annealing of the resulting the yttrium oxide nanoparticles are also described. The nitrate method produced net...

The condition of oligo-micelle formation of sodium di-isodecyl sulfosuccinate (SDIDS) emulsifier in hydroalcoholic solutions is used to study particle formation of vinyl chloride emulsion polymerization in a batch reactor. The change on micellization behavior was investigated by critical micelle concentration (CMC) and zeta potential parameters. To detect the occurrence of secondary nucleation ...

We investigated the influence of tetrahydrofuran (THF) addition on the structure of poly(1,2-butadiene-b-ethylene oxide) [PB-PEO] micelles in aqueous solution. Our studies showed that while the micelles remained starlike, the micelle core-corona interfacial tension and micelle size decreased upon THF addition. The detailed effects of the reduction in interfacial tension were probed using contra...

Pluronic based formulations are among the most successful nanomedicines and block-copolymer micelles including drugs that are undergoing phase I/II studies as anticancer agents. Using coarse-grained models, molecular dynamics simulations of large-scale systems, modeling Pluronic micelles interacting with DPPC lipid bilayers, on the μs timescale have been performed. Simulations show, in agreemen...