OBJECTIVES To explore differences in experiences of care reported in the Cancer Patient Experience Survey (CPES) between patients with cancer of unknown primary (CUP) and those with metastatic disease of known primary (non-CUP); to determine insights pertaining to the experiences of care for CUP respondents from free-text comments. DESIGN Two separate, but related, studies, involving secondar...

Post-meiotic transcription is widespread in mammalian spermatogenesis, but is generally believed to be absent from Drosophila spermatogenesis. Genes required during meiosis, in early spermatids or later in spermiogenesis are typically transcribed in primary spermatocytes in Drosophila. Their mRNAs are then stored in the cytoplasm until the protein product is needed. Recently, using in situ hybr...

BACKGROUND Some nonstemmed hip systems have been developed to avoid stress shielding and aseptic loosening, which are major drawbacks of stemmed hip arthroplasty. Without the stem, the cup over the femoral head can be stabilized by anatomic fitness of the cup interior and mechanical fixation of the auxiliary screws. METHODS Using finite-element method, neck-shaped systems with two bone-cup fi...

the aim of this paper is to develop a systematic method to analyze the effects of forming parameters on the quality of part formability and determine the optimal combination of the forming parameters for the sheet hydroforming process. in this paper, the effects of four important process parameters namely fluid pressure, friction coefficient at blank/punch interface, gap between die rim block a...

In the present study the bark of Plumeria alba Linn. (Apocynaceae) was evaluated for pharmacognostical and phytochemical parameters and methanolic extract for antimicrobial activity by determining its MIC (by checker board method) and zone of inhibition (by cup plate method).Pharmacognostical parameters of the bark of Plumeria alba Linn. (Apocynaceae) were studied with the aim of drawing the ph...