A retrospective study of the histopathological features of retinitis pigmentosa was undertaken. A consistent finding in 10 out of 10 eyes from 6 patients with retinitis pigmentosa was the presence of a preretinal membrane. The frequency of this finding has not been noted previously. Preretinal gliosis may well be responsible for the production of the abnormal glinting fundus reflex seen at the ...

PURPOSE To test alternative hypotheses concerning the mechanisms of rod degeneration in retinitis pigmentosa (RP). METHODS Full-field rod electroretinograms and rod visual fields were measured for 15 patients with RP and a normal control group. The rod a-wave was fitted with a computational model based on known transduction biochemistry. The values of td (the initial delay), S (a sensitivity ...

Patients with retinitis pigmentosa (RP) show delayed inner retinal responses as measured by the cone ERG response to a 30 Hz stimulus. To determine the extent to which this delay results from abnormalities of cone phototransduction, cone ERGs to single flashes were obtained from 21 patients with RP and a model of cone phototransduction was fitted to the leading edge of the a-waves of these ERGs...

PURPOSE To study the effects of acetazolamide on central and peripheral visual function in patients with retinitis pigmentosa (RP) who showed no evidence of macular edema. METHODS Thirteen patients with retinitis pigmentosa participated in a preliminary study. Measures of central and peripheral visual function were obtained before and after an 8 wk period on acetazolamide. An additional 10 pa...

A retrospective study of the histopathological features of retinitis pigmentosa was undertaken. A consistent finding in 10 out of 10 eyes from 6 patients with retinitis pigmentosa was the presence of a preretinal membrane. The frequency of this finding has not been noted previously. Preretinal gliosis may well be responsible for the production of the abnormal glinting fundus reflex seen at the ...

Background : Retinitis pigmentosa is an inherited heterogeneous group of retinal disorders represented by rod photoreceptors progressive dysfunction with subsequent cone degeneration and the pigment epithelium. The typical manifestations are loss visual field night blindness. Purpose purpose this study was to examine Amsler Grid on right left eyes, no scotomas metamorphopsia were found. Method ...

R etinitis pigmentosa (RP) is the most prevalent hereditary retinal degenerative disease. To date, approximately 40 loci and mutations in more than 25 genes have been identified as the cause of various types of RP. The gene for human oxygen regulated photoreceptor protein (RP1) encodes a protein of 2156 amino acids that is localised in the connecting cilia of both rod and cone photoreceptors. T...

background: causes of blindness in children vary according to the region and socioeconomic development. within a given country these causes vary with passage of time. this reflects different levels of socioeconomic development and provision of healthcare services. this cross-sectional study was undertaken to estimate the major causes of severe visual impairment in children and specially prevent...

BACKGROUND The purpose of this study was to observe the characteristic findings of spectral-domain optical coherence tomography (SD-OCT) images in the retinas of patients with retinitis pigmentosa and to evaluate their distribution patterns in the early and advanced stages of the disease. METHODS A total of 184 patients (368 eyes) with retinitis pigmentosa were observed using SD-OCT. We studi...