Background: Chronic myeloid leukemia (CML) is a myeloproliferative hematopoietic malignancy with a heterogeneous proliferation of hematopoietic cells in the bone marrow. The ocular manifestations are rare symptoms of CML. In this case report, a CML patient with retinal hemorrhage is reported as an uncommon symptom. Case presentation: A 35-year-old man was referred due to decreased right eye vi...

Currently, there is no cure for the permanent vision loss caused by degenerative retinal diseases. One of the novel therapeutic strategies aims at the development of stem cells (SCs) based neuroprotective and regenerative medicine. The main sources of SCs for the treatment of retinal diseases are the embryo, the bone marrow, the region of neuronal genesis, and the eye. The success of transplant...

PURPOSE To compare the foveal thickness (FT) parameters measured by Stratus optical coherence tomography (OCT) and Spectralis OCT in various retinal diseases and to construct conversion formulas between the two types of OCT devices. METHODS We examined 366 consecutive patients (475 eyes) with retinal diseases and 13 normal controls (13 eyes). The patients were categorized into eight retinal d...

after central nervous system (cns) injuries, the regeneration process does not work out well except for remyelination process. this remyelination capacity in cns can be mentioned as a worthy example of stem/precursor cell-mediated renewal process. remyelination in cns is mediated by schwann cells which act mainly as remyelinating agents in peripheral nervous system (pns) but several studies hav...

In the last decade retinal diseases have become prevalently in India and it is growing alarmingly. Fortunately, most of blindness are caused are preventable if treated at appropriate time. Early detection of such retinal diseases like diabetic retinopathy, macular degeneration, retinal detachment and glaucoma is very vital. Optical coherence tomography (OCT) is an In vivo imaging technique for ...

Retinal degenerative diseases are the leading causes of blindness worldwide. Replacing lost retinal cells via stem cell-based therapies is an exciting, rapidly advancing area of translational research that has already entered the clinic. Here, we review the status of these clinical efforts for several significant retinal diseases, describe the challenges involved and discuss how basic developme...

Teleophthalmology holds a great potential to improve the quality, access, and affordability in health care. For patients, it can reduce the need for travel and provide the access to a super-specialist. Ophthalmology lends itself easily to telemedicine as it is a largely image based diagnosis. The main goal of the proposed system is to diagnose the type of disease in the retina and to automatica...

Photoreceptor neuronal degenerations are common and incurable causes of human blindness with one in 2000 affected. Approximately, half of all patients are associated with known mutations in more than 200 disease genes. Most retinal degenerations are restricted to the retina (primary retinal degeneration) but photoreceptor degeneration can also be found in a wide variety of systemic and syndromi...

Retinal arterial macroaneurysms are acquired, focal dilation of a retinal artery. Patients with can present an acute or gradual loss vision as result vitreous hemorrhage, preretinal hemorrhage macular edema. An 81 year old female, known hypertensive since 12 years under regular follow-up visits, presented to us secondary ruptured artery macroaneurysm in the right eye. She was managed indirect a...

Knowledge about retinal photoreceptor signal transduction and the visual cycle required for normal eyesight has increased exponentially over the past decade. Substantial progress in human genetics has facilitated the identification of candidate genes and complex networks underlying inherited retinal diseases. Natural mutations in animal models that mimic human diseases have been characterized a...