We investigated the antifungal activities of itraconazole and voriconazole on Aspergillus species by time kill studies, and the results were compared with those obtained for Candida species. Exposure of Aspergillus fumigatus conidia to varying concentrations (1.25 to 10 microg/ml) of itraconazole and voriconazole resulted in cellular death; the cytocidal effect was time and concentration depend...

AIM OF THE STUDY The spectrum of pulmonary infections in patients with lung cancer is wide, and tools for target-oriented infection control measures are necessary. In this retrospective study we report the microbiological spectrum of pneumonia (based on the results of sputum culture) in a case series of Turkish patients with lung malignancies. MATERIAL AND METHODS Between 2010 and 2011 a tota...

wild grasses are the most important primary feedstuffs which are susceptible to contamination with toxigenic fungi belonging to aspergillus spp. in order to explore diversity of aspergillus species associated with the inflorescences of gramineous weeds, infected inflorescences were collected from wild grasses in western parts of iran. fifty-six aspergillus isolates were obtained from all diseas...

introduction: there are suspended fungal spores in the air and in the nasal mucosa of adults, especially in areas with a humid climate. several studies have revealed the role of fungi in the pathogenesis of chronic rhinosinusitis (crs) in recent years but it is a topic of controversy, especially in regions with low humidity. the aim of this study was to evaluate the prevalence of fungal species...

Azole resistance in Aspergillus fumigatus is increasingly reported. Here, we describe the validation of the AsperGenius, a new multiplex real-time PCR assay consisting of two multiplex real-time PCRs, one that identifies the clinically relevant Aspergillus species, and one that detects the TR34, L98H, T289A, and Y121F mutations in CYP51A and differentiates susceptible from resistant A. fumigatu...

Aspergillus fumigatus is the main etiologic agent of invasive aspergillosis (IA). Other Aspergillus species belonging to the section Fumigati (A. fumigatus complex) may occasionally be the cause of IA. These strains are often misidentified, as they cannot be distinguished from A. fumigatus by conventional morphological analysis and sequencing methods. This lack of recognition may have important...

Objective:Mold contamination of cakes and the possibility of mold growth can pose a serious health problem. Bakery products include various ingredients, which regularly contain molds. These microorganisms on cakes can come from the air, contaminated packaging materials and other sources.Methods: In this study, a total of 500 fungal isolates representing 36 species, were identified from cake sam...