Botrytis cinerea, a pathogenic fungus that causes necrosis in plants, is one of the most destructive pathogens hazelnuts. This responsible for causing Husk Brown Rot, significant threat to hazelnut production. The plant’s defense mechanism against this pathogen, as well other pathogens, complex biological process involves changes at molecular, biochemical, and physiological levels. To better un...

The occurrence and spreading of multidrug resistance in bacterial pathogens represent one the greatest challenges 21st century. With fewer new antibiotics development, novel unconventional concepts drug development formulation need to be explored overcome global crisis. Biomedical nanotechnology offers promising strategies for reformulation established such a way that they regain their activity...

ObjectivesMeningitis in neonates and young infants leads to significant morbidity mortality worldwide. This study aimed investigate pathogens, antibiotic resistance secular change of incidence Hong Kong.MethodsA retrospective search was performed on meningitis aged <3 months three Kong public hospitals from 2004 2019. Medical charts were reviewed, with focus the identification pathogens.Results...

In Korea, vancomycin-resistant enterococci have become important nosocomial pathogens since the late 1990s, and most vancomycin-resistant enterococcal isolates have been VanA phenotype-vanA genotype strains. In 2001, we experienced an outbreak of VanB phenotype-vanA genotype vancomycin-resistant enterococci at a university hospital. This is the first report of VanB-vanA vancomycin-resistant ent...

The SENTRY Program was established in January 1997 to measure the predominant pathogens and antimicrobial resistance patterns of nosocomial and community-acquired infections over a broad network of sentinel hospitals in the United States (30 sites), Canada (8 sites), South America (10 sites), and Europe (24 sites). During the first 6-month study period (January to June 1997), a total of 5,058 b...

OBJECTIVE The rising occurrence of drug-resistant pathogens accentuates the need to identify novel antibiotics. We wanted to identify new scaffolds for drug discovery by repurposing FDA-approved drugs against Acinetobacter baumannii, an emerging Gram-negative nosocomial drug-resistant pathogen. MATERIALS AND METHODS In this study, we screened 1040 FDA-approved drugs against drug-susceptible A...

Antimicrobial resistance is a major public health crisis. The prevalence of drug-resistant organisms, such as the emerging NAP1 strain of Clostridium difficile, now highly resistant to fluoroquinolones, Acinetobacter species, Klebsiella pneumoniae carbapenemase-producing organisms, and methicillin-resistant Staphylococcus aureus, is increasing nationwide. The sources of antimicrobial resistance...

Healthcare-associated infections affect 1.4 million patients at any time worldwide, as estimated by the World Health Organization. In intensive care units, the burden of healthcare-associated infections is greatly increased, causing additional morbidity and mortality. Multidrug-resistant pathogens are commonly involved in such infections and render effective treatment challenging. Proper hand h...

Urinary tract infection is one of the common clinical condition in the patients presenting to the clinics and hospitals. Detection of common pathogens and their antimicrobial susceptibility pattern is mandatory for effective treatment. The present study was conducted to detect common pathogens of urinary tract infection (UTI) and their susceptibility pattern to the commonly used antimicrobial a...

Introduction: The aims of this study were to review the pathogens associated with nosocomial infections in a surgical intensive care unit of an university hospital in Turkey and to summarize rates of antimicrobial resistance in the most common pathogens. Methods: This study was an observational survey involving patients with a potential risk for nosocomial infections and was performed over a pe...