Introduction: Since the incidence of various infections caused by Staphylococcus aureus increases, the use of effective antibiotics such as clindamycin has been growing to treat the systemic and local infections caused by such organisms. Antibiotic-resistant species are emerging and spreading in today's communities due to misuse of antibiotics and incomplete treatment, turning into a serious ch...

Background: Infections are one of the most important causes of death in infants, especially in developing countries. Inappropriate use and administration of antibiotics can contribute to the resistance and spread of infection. In this study, we determined the antibiotic resistance pattern of the bacteria isolated from clinical samples of blood, cerebrospinal fluid, and urine in the neonatal int...

Recreational waters should be considered as risks for Enterococcal infections in regions with high utilization and long exposure periods. The aim of this study was to investigate the resistance of Enterococci to selected antibiotics and some heavy metals [Pb+2, Fe+2, Zn+2 and Cr+2]. A total of 75 Enterococcal isolates was obtained from 54 bathing and ...

The introduction of antimicrobial drugs in medicine gave hope for a future in which all infectious diseases could be controlled. Decades later it appears certain this will not be the case, because antibiotic resistance is growing relentlessly. Bacteria possess an extraordinary ability to adapt to environmental challenges like antimicrobials by both genetic and phenotypic means, which contribute...

All professionals who are concerned about the health of children need to be aware of the significance of recent developments in bacterial resistance to antibiotics. This seemingly esoteric area has become a major problem that the Centers for Disease Control has labeled a public health emergency. We professionals have caused the problem. Antibiotics became available for general use in the 1940s ...

background and objectives: pseudomonas aeruginosa (pa) is one of the most important causes of nosocomial infections and has an intrinsic resistance to many antibiotics. among all the resistance-nodulation-division (rnd) pumps of p. aeruginosa, mexab-oprm is the first efflux pump found to target multiple classes of antibiotics. this study was aimed to evaluate the expression level of genes expre...

Escherichia coli are beneficial bacteria found in human intestinal tracts. However, certain E. coli strains are pathogenic and can cause serious infections, such as neonatal sepsis and meningitis. The goal of this work is to create an awareness of the phenomenon of bacterial adaptation to antibiotics. We demonstrate that the pre-exposure of E. coli to low levels of antimicrobial agents (inducer...