نتایج جستجو برای: repopulation index

تعداد نتایج: 397662  

Journal: :Nucleic acids research 2002
Francisca Diaz Maria Pilar Bayona-Bafaluy Michele Rana Marialejandra Mora Huiling Hao Carlos T Moraes

Partially-deleted mitochondrial DNA (DeltamtDNA) accumulates during aging of postmitotic tissues. This accumulation has been linked to decreased metabolic activity, increased reactive oxygen species formation and the aging process. Taking advantage of cell lines with heteroplasmic mtDNA mutations, we showed that, after severe mtDNA depletion, organelles are quickly and predominantly repopulated...

1999
SANJEEV GUPTA CHARLES E. ROGLER

Gupta, Sanjeev, and Charles E. Rogler. Lessons From Genetically Engineered Animal Models. VI. Liver repopulation systems and study of pathophysiological mechanisms in animals. Am. J. Physiol. 277 (Gastrointest. Liver Physiol. 40): G1097–G1102, 1999.—The ability to localize transplanted hepatocytes in the liver offers exciting new opportunities. Transplanted hepatocytes enter liver plates, form ...

Journal: :Blood 1982
C Eastment E Denholm I Katsnelson E Arnold P O Ts'o

Experiments on long-term murine bone marrow cultures indicate that the production and maintenance of the hematopoietic stem cell is dependent on the establishment of an adherent monolayer and a secondary repopulation of the culture with fresh marrow. In contrast, we have found that bone marrow cultures derived from the Syrian hamster do not require a repopulation step and produce stem cells tha...

2016
Samriddha Ray Norika Chiba Changfu Yao Xiangrong Guan Alicia M. McConnell Brian Brockway Loretta Que Jonathan L. McQualter Barry R. Stripp

Recent studies have implicated keratin 5 (KRT5)+ cells in repopulation of damaged lung tissue following severe H1N1 influenza virus infection. However, the origins of the cells repopulating the injured alveolar region remain controversial. We sought to determine the cellular dynamics of lung repair following influenza infection and define whether nascent KRT5+ cells repopulating alveolar epithe...

Journal: :Brazilian Archives of Biology and Technology 2016

خاکی, آرش, خیاط‌نوری, میرهادی, صراطی‌نوری, حامد, صفوی, سید اسماعیل,

  Background and Aim: Methotrexate (MTX) as a chemotherapeutic agent is used for the treatment of a variety of tumors and inflammatory diseases. Different studies have shown that methotrexate has inhibitory effects on oogenesis and spermatogenesis, and causes impair fertility and different pathological changes in testis of laboratory animals. The aim of this study is to investigate the effect o...

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