At a time when the value of performing aortic valve replacement surgery on elderly patients with aortic stenosis (AS) was being questioned, we reported our findings of a formal decision analysis entitled “You’re Never Too Old” (1) that revealed survival benefit of surgical aortic valve replacement (SAVR) in symptomatic elderly AS patients. SAVR is currently widely accepted as a treatment of oth...

Chiffon cakes prepared with a mixture of wheat flour / konjac flour / soy protein isolate (SPI) (89.5 : 0.5 : 10 ) together with replacement of 50-70% soybean oil with water were investigated for their physicochemical and sensory properties. Moisture and protein content in reduced-fat chiffon cakes were significantly higher (p < 0.05) than the control chiffon cake. Specific volume decreased (p ...

AIMS Since redesign of the Oxford phase III mobile-bearing unicompartmental knee arthroplasty (UKA) femoral component to a twin-peg design, there has not been a direct comparison to total knee arthroplasty (TKA). Thus, we explored differences between the two cohorts. PATIENTS AND METHODS A total of 168 patients (201 knees) underwent medial UKA with the Oxford Partial Knee Twin-Peg. These pati...

We retrospectively evaluated correlations between cardiac manifestations and globotriaosylceramide (Gb3) accumulation in cardiomyocytes from Taiwanese patients with Fabry disease and the IVS4+919G>A (IVS4) mutation who underwent endomyocardial biopsy (Shire; Fabry Outcome Survey data; extracted January 2015). Of 24 males and six females (median age [Q1; Q3] at biopsy 60.4 [57.4; 64.1] and 61.3 ...

4-{[(4-Cyanophenyl)(4H-1,2,4-triazol-4-yl)amino]methyl}phenyl sulfamate and its ortho-halogenated (F, Cl, Br) derivatives are first-generation dual aromatase and sulfatase inhibitors (DASIs). Structure-activity relationship studies were performed on these compounds, and various modifications were made to their structures involving relocation of the halogen atom, introduction of more halogen ato...

Capital cost, resale value and running cost including maintenance costs, repairing costs, and operation costs of equipment are considered as crisp numbers in ordinary replacement problem. Nevertheless, in a special situation such as operating military equipments during wartime, the working efficiency of the machine and its related costs are no longer crisp but uncertain. This uncertainty can be...

BACKGROUND The goal of total hip arthroplasty (THA) is optimal pain relief and a normalized health-related quality of life. Anxious patients describe more pain and more difficulties than non-anxious patients during rehabilitation after THA. The aims of the present study were twofold: (1) to identify vulnerable patients using the general self-efficacy scale (GSES) and the Tampa scale for Kinesio...