Each year in Niger, more than 40% of children under 5 years suffer from chronic malnutrition and 10% acute malnutrition. The national nutrition rehabilitation protocol encourages the use local foods. objective this work is to analyze impact supplementation Moringa oleifera. We conducted a randomized double-blind clinical trial 400 with moderate (MAM) aged 6 59 months admitted outpatient nutriti...

Background and objectives: The present work aimed to evaluate the acute toxicity of Aeollanthus pubescens essential oil, whose antimicrobial activity has been proven in vitro by previous studies and to examine the effects of this essential oil on the biochemical parameters (transaminases ALT and AST, urea, creatinine and cholesterol) and hematological and histological ...

Background and Aims: Mercury, with its oxidative activity, causes damage to the antioxidant enzymes thus resulting in physiological disorders. Sodium selenide is an antioxidant that protects antioxidant enzymes. The aim of this study was to investigate the protective effect of sodium selenide on renal toxicity induced by mercuric chloride in rats. Materials and Methods: Animals were divided in...

Methotrexate (MTX) is used to treat various disorders and can be safely administered at high doses if renal function is adequate, high urine output (UOP) is maintained, urine is alkalinized and leucovorin rescue is given. Despite those measures, toxicity (mucositis, diarrhea, renal dysfunction and myelosuppression) occurs with prolonged high serum drug concentrations [1]. Dialysis-based methods...

The authors present a case of Trimethoprim-sulfamethoxazole-induced hyperkalemia in a patient with normal renal function. While toxicity of this drug has been reported in patients with renal insufficiency, this case highlights the toxicity associated with normal kidney function. Due to its popularity in the medical field and to the largely unrecognized effect of hyperkalemia, it is important to...

Deltamethrin is -cyano pyrethroid insecticide used extensively in pest control. Although initially thought to be least toxic, a number of recent reports showed its toxicity in mammalian and non-mammalian laboratory and wildlife animal species. Lycopene is the pigment that gives tomatoes their red color and is one of four main carotenoids normally found in human blood and tissue. The present stu...

method of glomerular filtration rate (clearance rate of the endogenous creatinine). Like low dose (11 mg/kg) of adefovir, low dose of tenofovir only also caused minor effects on the renal structure while higher doses of tenofovir caused severely gastrointestinal toxicity within 2 weeks. No renal toxicity was seen for either entecavir or telbivudine, highlighting a high degree of safety compared...

Ethyl methanesulfonate is a mutagenic, alkylating agent and considered harmful to humans at levels greater than a certain threshold; however, the toxicity at high doses remains unclear. We report a case of a Japanese man who presented with status epilepticus, rhabdomyolysis, pancytopenia, and hair loss after accidental ingestion of a massive amount of ethyl methanesulfonate. The patient complet...