PURPOSE To quantify the hemodynamic impact of a flared renal stent on the performance of fenestrated stent-grafts (FSGs) by analyzing flow patterns and wall shear stress-derived parameters in flared and nonflared FSGs in different physiologic scenarios. METHODS Hypothetical models of FSGs were created with and without flaring of the proximal portion of the renal stent. Flared FSGs with differ...

the angiotensin 1-7 (ang 1-7), is abundantly produced in kidneys and antagonizes the function of angiotensin ii through mas receptor (masr) or other unknown mechanisms. in the current study, the role of masr and steroid hormone estrogen on renal blood flow response to ang 1-7 administration was investigated in ovariectomized (ov) female rats. ov female wistar-rats received estradiol (500 µg/kg/...

BACKGROUND/AIMS Renal blood flow (RBF) is tightly regulated by several intrinsic pathways in maintaining optimal kidney blood supply. Using a rat model of aortocaval (AC) fistula, we investigated remodeling of the renal artery following prolonged increased blood flow. METHODS An AC fistula was created in the infrarenal aorta of anesthetized rats, and changes of blood flow in the renal artery ...

Background and objectives: Many clinicians believe that low-dose dopamine (LDD) [2 g/kg/min] increases renal blood flow (RBF) and medium-dose norepinephrine (MD-NE) [0.4 g/kg/min] decreases RBF. They also believe that MD-NE might induce mesenteric and/or coronary ischemia. In fact, the effects of these drugs on renal and vital organ blood flow are poorly understood. The aim of this study was to...

Previous studies suggest that hypoxia and hypercapnic acidosis exert a renal nerve mediated adverse effect on renal haemodynamic function. We therefore examined the effect of hypoxia and hypercapnic acidosis on renal blood flow and glomerular filtration rate responses to lowering renal perfusion pressure from 125 to 75 mmHg in the anaesthetized dog. To study the role of renal nerves in these re...

Joule-Thomson cooling systems are used in refrigeration processes such as cryogenic gas liquefaction. Although extensive studies have been carried out by researchers, most of them include cryogenic heat exchangers and their associated fields. In the current study, an attempt was made to indicate the effect of using inappropriate operational conditions in a cryogenic Joule-Thomson cooling system...

Intrarenal angiotensin (AII) infusion results in a poorly sustained renal vasoconstrictor response. To examine the relationship between fade and renal tachyphylaxis to AII, sub-pressor doses of AII and norepinephrine (NE) were injected into the renal arteries of anesthetized dogs, resulting in a transient reduction (greater than 50 percent) in renal blood flow. Continuous intrarenal AII infusio...