Background: Prolonged use of cyclosporine A for prevention of allograft rejection is associated with nephrotoxicity development. Naringenin and olive oil are beneficial dietary antioxidants with potential renoprotective properties. This study aimed to evaluate the therapeutic effect of naringenin and olive oil in alleviating cyclosporine induced nephrotoxicity in rats by the assessment of renal...

Certain benefits are clearly associated with the use of off-pump coronary artery bypass grafting (CABG) as compared with the on-pump CABG. The superiority is more evident in patients with multiple co morbidities including renal failure.We reviewed the medical records of a 67-year-old male with a past medical history that was significant for multiple cardiovascular diseases and new-onset end-sta...

Aims: Renal vascular clamping during partial nephrectomy can lead to renal ischemia and kidney damage due to reperfusion injuries, but a surgical technique without any ischemia can eliminate such unwanted effects on kidney function. The present study aimed to demonstrate the feasibility of partial nephrectomy in conditions where the renal artery is ready to be clamped. Patient Information: In ...

heart failure is common in patients with chronic renal disease, either as a complication of renal failure or from shared risk factors, or is the major cause of death in patients on dialysis. at present, end stage renal disease (esrd) patients who have systolic heart failure are considered high-risk for surgery; and nephrologists and cardiologists are reluctant to refer these patients for kidney...

Objective: Thrombotic thrombocytopenic purpura (TTP) is the most malignant variant of microangiopathy that usually presents by typical symptoms including thrombocytopenia, hemolytic anemia, neurological abnormalities, fever and renal impairment. Report of the Case: We report a 12-year-old male presented by cytopenia, fever, purpura on his extremities, seizure and lethargy. Peripheral blood sm...

The present study was aimed to evaluate the beneficial effect of Cystone syrup in an experimental model of glycerol-induced acute renal failure (ARF) in rats. Biochemical parameters, kidney weight and histopathological evaluation were performed to conclude the beneficial effect of Cystone syrup. Administration of single dose of 50% v/v glycerol (8ml/kg.i.m) caused severe renal dysfunction assoc...

Introduction: Ischemia/reperfusion (IR) injury involves a complex interrelated sequence of events. High levels of nitric oxide (NO) are generated with inducible form of nitric oxide synthase (iNOS) leading to the renal IR injury and glutathione (GSH) depletion. The present study was designed to investigate the effect of L-Nil (N6- (1-Iminoethyl)-L- lysine.hydrochloride), a selective inhibito...

Background: There is no curative treatment for chronic renal failure (CRF). Important strategies for the control and prevention of the advancement of CRF are increased renal function and decreased blood pressure (BP) and weight. Borage has many benefits, such as increased frequency of urination, decreased BP, and increased renal function. This clinical trial study was designed to determine the ...

vesicoureteral reflux (vur) is one of the most important causes of urinary tract infection and renal failure in children. it is a potentially self-limited disease. the aim of this study was to evaluate the clinical course and significant factors in children with primary vur. the medical charts of 125 infants and children (27.2 % males, 72.8% females) with all grades of primary vur were retrospe...