background: the development of injectable sustained-release products are of great interest to veterinary pharmaceuticals and animal health business. recently, great attention has been paid to in situ gel-forming chitosan/beta-glycerophosphate (chitosan/β-gp) solutions due to their good biodegradability and thermosensitivity. objectives: the general aim of this study was to prepare a novel in si...

the most frequent adverse effects of indomethacin like other nsaids are gastro–intestinal and central nervous system disturbances. extended release or enteric release formulations minimize these symptoms. the objective of this study was to develop an extended release pellet formulation of indomethacin by the centrifugation (rotary fluid bed granulation) or powder layering method. layered, nonpa...

in recent years, great efforts have been devoted to the design of drug delivery systems. many polymeric excipients have been studied in order to make drug release fit the desired profiles. the aim of this work was to design a theophylline oral suspension, as sustained release pharmaceutical preparation in order to decrease the plasma level fluctuations and adverse effects of theophylline. micro...

background: to explain the role of arthroscopic release in intractable frozen shoulders. we used different questionnaires and measuring tools to understand whether arthroscopic release is the superior modality to treat patients with intractable frozen shoulders. methods: between 2007 and 2013, in a prospective study, we enrolled 80 patients (52 females and 28 males) with recalcitrant frozen sho...

i ntroduction: due to the increase in le fort surgeries and its effect on nose widening, it seems necessary to use an alternative method without this effect. the present research examined the effect of alar release on interalar changes in le fort i osteotomy. m at erials and methods: the study population included patients admitted to bou-ali hospital in 2012-2013 undergoing le fort i osteotomy....

introduction: today, with development of various industries, the adverse events originated from explosion and emission of toxic and chemical substances have increased. these events may cause serious environmental problems that threaten human health and safety. therefore, knowledge about the risk of toxic substances from industrial facilities is essential. although, chlorine is extensively utili...

in this study, tretinoin microemulsion has been formulated based on phase diagram studies by changing the amounts and proportions of inactive ingredients, such as surfactants, co-surfactants and oils. the effects of these variables have been determined on microemulsion formation, particle size of the dispersed phase and release profile of tretinoin from microemulsion through dialysis membrane. ...

the purpose of this study was to prepare and characterize nimodipine loaded microspheres using ethyl cellulose (ec) as a carrier polymer through an emulsion solvent evaporation method. these evaluations characterized the pattern of drug release from prepared microspheres. nimodipin loaded microspheres were prepared using an emulsification solvent evaporation method. the effect of process variab...

© 2002 Kaiser Foundation Health Plan of Washington. All Rights Reserved. Back to Top Kaiser Foundation Health Plan of Washington Clinical Review Criteria Home INR Monitoring NOTICE: Kaiser Foundation Health Plan of Washington and Kaiser Foundation Health Plan of Washington Options, Inc., provide these Clinical Review Criteria for internal use by their members and health care providers. The Clin...

© 2002 Kaiser Foundation Health Plan of Washington. All Rights Reserved. Back to Top Kaiser Foundation Health Plan of Washington Clinical Review Criteria Home INR Monitoring NOTICE: Kaiser Foundation Health Plan of Washington and Kaiser Foundation Health Plan of Washington Options, Inc., provide these Clinical Review Criteria for internal use by their members and health care providers. The Clin...