A cold-adapted marine alkaline protease (MP, accession no. ACY25898) was produced by a marine bacterium strain, which was isolated from Yellow Sea sediment in China. Many previous researches showed that this protease had potential application as a detergent additive. It was therefore crucial to determine the tertiary structure of MP. In this study, a homology model of MP was constructed using t...

We prove that Khovanov homology detects the trefoils. Our proof incorporates an array of ideas in Floer and contact geometry. It uses open books; invariants we defined instanton setting; a bypass exact triangle sutured homology, proven here; Kronheimer Mrowka's spectral sequence relating with singular knot homology. As byproduct, also strengthen result Mrowka on $SU(2)$ representations group.

The taxonomic relationship between some hypha-forming Cryptococcus neoformans strains and those that morphologically fit the standard description of this species was determined on the basis of DNA base ratios and DNA-DNA duplex formation. The average guanosine plus cytosine content, as estimated from melting temperature profiles, varied between 43.0 and 45.9% for all C. neoformans strains exami...

osmotic stress is one of the major factors that significantly reduce yields in dry areas. plants respond to this abiotic stress at physiological and molecular levels. many genes are induced under stress conditions by transcription factors. dehydration responsive element binding (dreb) protein is a subfamily of ap2/erf transcription factors which control expression of many osmotic stress-inducib...

Working in the context of symmetric spectra, we describe and study a homotopy completion tower for algebras and left modules over operads in the category of modules over a commutative ring spectrum (e.g., structured ring spectra). We prove a strong convergence theorem that for 0-connected algebras and modules over a (−1)-connected operad, the homotopy completion tower interpolates (in a strong ...

objective: crispr/cas9 technology provides a powerful tool for targeted modification of genomes. in this system, a donor dna harboring two flanking homology arms is mostly used for targeted insertion of long exogenous dna. here, we introduced an alternative design for the donor dna by incorporation of a single short homology arm into a circular plasmid. materials and methods: in this experiment...

modeling and simulation techniques are now widely used alongside with their experimental counterparts in order to complement them, or sometimes to bring first insights into the possible outcome of experiments. “modeling” is a general word that could encompass a wide range of methods that could be applied to a variety of subjects and problems. here, the use of selected molecular modeling methods...

Two structures are called homologous if they represent corresponding parts of organisms which are built according to the same body plan (23, 33). The existence of corresponding structures in different species is explained by derivation from a common ancestor that had the same structure as the two species compared (25, 35). The eye of a cow is homologous to the eye of a fish but not to the eye o...