BACKGROUND Persons with multiple sclerosis (MS) are often physically inactive and sedentary. This observation has prompted the search for modifiable variables derived from established theories that act as correlates of physical activity. Such variables would presumably represent targets for interventions designed to promote change in physical activity behavior among persons with MS. The current...

MS affects about one million people worldwide and causes physical and cognitive disability. There are three types of MS: relapsing-remitting, secondary progressive and primary progressive, that differ in the dynamical patterns of disease progression. There are as yet no known cures for MS. Patients with relapsing MS are currently treated with drugs that exert immunomodulatory effects and slow t...

Metabolic Glycoengineering Immune checkpoint ligand functionalized Schwann cells have great potential to treat multiple sclerosis. In article number 2107392, Kin Man Au, Andrew Z. Wang, and Roland Tisch bioengineer with programmed death 1 (PD-L1) cluster of differentiation 86 (CD86) prevent ameliorate established mouse models chronic relapsing–remitting experimental autoimmune encephalomyelitis...