Polycystic Ovary Syndrome is a chronic endocrine disorder with clinical manifestations of oligomenorrhoea, amenorrhea, hirsuitism, ovarian dysfunction, and multiple cysts, affecting many women reproductive age. PCOS the primary cause ovulatory infertility worldwide. This study assessed concentration hormones in polycystic syndrome patients attending tertiary hospitals Niger Delta Region, Nigeri...

Mean plasma levels of prolactin (PRL), placental lactogen (OCS) and luteinizing hormone (LH) have been studied in pregnant ewes at different times of the year from approximately day 60 of gestation until parturition. Three groups were constituted and inseminated at different times: September, group I; November, group II; March, group III. Blood samples were collected on two consecutive days app...

Background: Mammalian Cell lines are the main expression system for the production of recombinant therapeutic proteins. Optimization of cell culture condition is performed via alteration in different parameter. Cell culture media plays an important role in cell cycle because of compounds such as amino acids, vitamins, inorganic salts, glucose, and serum as a source of growth factors, trace elem...

By using immunohistochemistry and in situ hybridization, we have demonstrated that the nitric oxide (NO)-synthesizing enzyme NO synthase is present in gonadotrophs and in folliculo-stellate cells of the anterior pituitary gland of male and female rats. A marked increase in levels of NO synthase protein and mRNA was observed after gonadectomy. In vitro studies on dispersed anterior pituitary cel...

Indeed, optio is Weaver who is credited with the origin of the term molecular biology in 1938. Development of luteinizing hormone releasing hormone neurones.

In Wsh, luteinizing hormone (LH) stimulates processes leading to Wnal oocyte maturation and ovulation in females, and spermiation in males. The hormone is a heterodimeric glycoprotein composed of two non-covalently associated subunits. In this study, we describe the expression of tilapia LH (tLH) as a biologically active, single-chain polypeptide using the methylotrophic yeast Pichia pastoris. ...

The glycoprotein hormones of the anterior pituitary and of the placenta are made up of a and p subunits, one of which, the a, is common to each hormone. Thcy therefore share some similar physicochemical and immunological properties, and the complete purification of follicle-stimulating hormone, for instance, has proved difficult. Many preparations which have appeared to be pure by one criterion...