BACKGROUND: Erythropoietin (EPO) is the main stimulator of erythropoiesis, but EPO also has non-hematopoietic effects. The recent data show positive effects on tissue regeneration. AIM: This review aims to know highlights pathophysiological mechanisms at different stages regeneration, and possible clinical applications in wound healing. METHODS: A literature considering reviews, studies, origin...

Thrombopoietin (TPO), the ligand for c-mpl, is a novel cytokine comprising an amino terminal domain with homology to erythropoietin and a glycosylated carboxyl terminal domain that does not bear overall homology to other known proteins. We report the cloning of cDNAs encoding the porcine and murine TPO and the characterization of the human TPO gene. The cDNA for an additional splice form (TPO-2...

The principal objective of the evaluation activity set in train with the reform of the Structural Funds was quite clearly to improve the effectiveness of Community structural operations. It was therefore considered of fundamental importance, among other measures, to strengthen and extend the traditional evaluation practice of the Member States, which consequently should be made an element of pa...

  Background:The dynamic binding capacity (DBC) of a chromatography matrix in protein purification is the amount of the total protein absorbed into the matrix, before occurrence of a significant break in the breakthrough curve. Optimization of the process criteria for maximum DBC avoids extra process scale-up and reduces ...

Pasien COVID-19 memiliki gejala bervariasi. Saat ini, selain ditemukan pada sistem pernapasan dan pencernaan, di organ lain pun mulai banyak ditemukan, salah satunya saraf dengan neurologis yang bervariasi seperti anosmia (sering), stroke, nyeri kepala, kejang, penurunan fungsi kognitif. Tata laksana pasien kognitif masih diteliti. Beberapa pilihan terapi antaranya human recombinant erythropoie...