نتایج جستجو برای: recombinant erythropoietin red cell metabolism
تعداد نتایج: 2036318 فیلتر نتایج به سال:
The introduction of recombinant human erythropoietin (epoetin) transformed the management of anaemia for the vast majority of dialysis patients. The immediate benefit of transfusion-independence was a lower risk of contracting blood-borne infections and iron overload. The raised haematocrit led to improvements in quality of life, which in turn has been associated with improved long term surviva...
We report a 3-year case history that describes a 78-year-old woman with recurrent transfusion-dependent pure red cell aplasia (PRCA) secondary to recombinant epoetin use that was responsive to immunosuppressant therapy. The patient had kidney disease of unknown aetiology (estimated glomerular filtration rate of 13 ml/min/1.73 m2) and was not on dialysis. After 16 months of therapy with subcutan...
Sir, We read with interest the article recently published in Iranian Journal of Kidney Diseases, titled “Effect of Erythropoietin on Kidney Allograft Survival: Early Use After Transplantation” by Yassari and colleagues.1 This study focused on the impact of recombinant human erythropoietin on graft survival during the six months after kidney transplantation. In a univariable analysis, they concl...
Erythroid burst-forming units are present in large numbers in infants with the anemia of prematurity. The erythroid progenitors respond normally in vitro to recombinant human erythropoietin (rHuEpo) (1). Although the mean hematocrit is considerably lower in premature infants than in adults, the mean serum erythropoietin concentration in the infants may not be any different from that in the adul...
The principal objective of the evaluation activity set in train with the reform of the Structural Funds was quite clearly to improve the effectiveness of Community structural operations. It was therefore considered of fundamental importance, among other measures, to strengthen and extend the traditional evaluation practice of the Member States, which consequently should be made an element of pa...
Several clinical trials in oncology have reported increased mortality or disease progression associated with erythropoiesis-stimulating agents. One hypothesis proposes that erythropoiesis-stimulating agents directly stimulate tumor proliferation and/or survival through cell-surface receptors. To test this hypothesis and examine if human tumors utilize the erythropoietin receptor pathway, the re...
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