نتایج جستجو برای: rb 255

تعداد نتایج: 19434  

Journal: :Genome Biology 2002

Journal: :Journal of Geography (Chigaku Zasshi) 1986

Journal: :Cancer research 1994
J Christoffersen E B Smeland T Stokke K Taskén K B Andersson H K Blomhoff

Elevated cyclic AMP levels induce a rapid block in the mid-G1 phase of the cell cycle in B-lymphoid Reh cells, accompanied by a transient block in G2. The retinoblastoma (Rb) gene product has been implicated as a key regulator of eukaryotic cell growth. The Rb protein enforces its growth-suppressive effect in early G1, where it is underphosphorylated and firmly bound in the nucleus. A possible ...

2017
Xiaonan Qiu Laura E. Pascal Qiong Song Yachen Zang Junkui Ai Katherine J. O’Malley Joel B. Nelson Zhou Wang

Elongation factor, RNA polymerase II, 2 (ELL2) is expressed and regulated by androgens in the prostate. ELL2 and ELL-associated factor 2 (EAF2) form a stable complex, and their orthologs in Caenorhabditis elegans appear to be functionally similar. In C. elegans, the EAF2 ortholog eaf-1 was reported to interact with the retinoblastoma (RB) pathway to control development and fertility in worms. B...

Journal: :The Journal of clinical investigation 2010
Ankur Sharma Wen-Shuz Yeow Adam Ertel Ilsa Coleman Nigel Clegg Chellappagounder Thangavel Colm Morrissey Xiaotun Zhang Clay E S Comstock Agnieszka K Witkiewicz Leonard Gomella Erik S Knudsen Peter S Nelson Karen E Knudsen

Retinoblastoma (RB; encoded by RB1) is a tumor suppressor that is frequently disrupted in tumorigenesis and acts in multiple cell types to suppress cell cycle progression. The role of RB in tumor progression, however, is poorly defined. Here, we have identified a critical role for RB in protecting against tumor progression through regulation of targets distinct from cell cycle control. In analy...

Journal: :Cancer research 2004
Xintao Wang Haiyun Deng Indranil Basu Liang Zhu

Re-expression of a tumor suppressor in tumor cells that lack it is an effective way to study its functional activities. However, because tumor cells contain multiple mutations, tumor suppressor functions that are dependent on (an)other regulators are unlikely to be identified by its re-expression alone if the other regulators are also mutated. In this study, we show that re-expression of retino...

2011
GUS SCHRADER

The purpose of this term paper is to give an accessible exposition of Fay’s trisecant identity [1]. Fay’s identity is a relation between the theta function and the cross-ratio function associated to a compact Riemann surface [2]. Although the majority of the paper will consist of developing the machinery needed to define these objects, let us briefly say a few words about some familiar objects ...

Journal: :CoRR 2013
Ashish Jain Narendra S. Chaudhari

We observed few important facts that concerns with the new proposal of knapsack cipher 0/255, recently published by Pham [1]. The author claimed that the time complexity for solving new improved trapdoor knapsack is O(256). In this paper, we show that the knapsack cipher 0/255 can be solved in the same time that is required for solving the basic knapsack-cipher proposed by Merkle and Hellman [2...

Journal: :Journal of Palliative Medicine 2012

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