نتایج جستجو برای: ran

تعداد نتایج: 9987  

2016
Hiu-Fung Yuen Ka-Kui Chan Angela Platt-Higgins El-Habib Dakir Kyle B. Matchett Yusuf Ahmed Haggag Puthen V. Jithesh Tanwir Habib Ahmed Faheem Fennell A. Dean Richard Morgan Philip S. Rudland Mohamed El-Tanani

It has been shown previously that cancer cells with an activated oncogenic pathway, including Met activation, require Ran for growth and survival.Here, we show that knockdown of Ran leads to a reduction of Met receptor expression in several breast and lung cancer cell lines. This, in turn suppressed HGF expression and the Met-mediated activation of the Akt pathway, as well as cell adhesion, mig...

2001
Nina Balagurova Stanislav Drozdov Svetlana Grabovik

Balagurova, N., Institute of Biology, Carelian Research Centre RAN, Laboratory of Plant Stress Physiology, Pushkinskaya, 11, Petrozavodsk, 185610 Russia Drozdov, N., Institute of Biology, Carelian Research Centre RAN, Laboratory of Ecological Plant Physiology, Pushkinskaya, 11, Petrozavodsk, 185610 Russia Grabovik, N., Institute of Biology, Carelian Research Centre RAN, Laboratory of Mire Ecosy...

Journal: :IEEE Transactions on Mobile Computing 2022

Cellular networks are undergoing a radical transformation toward disaggregated, fully virtualized, and programmable architectures with increasingly heterogeneous devices applications. In this context, the open architecture standardized by O-RAN Alliance enables algorithmic hardware-independent Radio Access Network (RAN) adaptation through closed-loop control. introduces Machine Learning (ML)-ba...

2014
Kohei Hasegawa Barry E. Brenner Sunday Clark Carlos A. Camargo

This study was designed to determine the percentage of asthma-related emergency department (ED) visits made by patients who recently ran out of their inhaled short-acting beta-agonists or inhaled corticosteroids and to characterize this understudied patient population. A secondary analysis was performed of data from four ED-based multicenter studies of acute asthma during 1996-1998 (n = 64 EDs)...

2014
Katia Y. Cáceres-Gorriti Euridice Carmona Véronique Barrès Kurosh Rahimi Isabelle J. Létourneau Patricia N. Tonin Diane Provencher Anne-Marie Mes-Masson

PURPOSE Epithelial ovarian cancer has the highest mortality rate of all gynecological malignancies. We have shown that high RAN expression strongly correlates with high-grade and poor patient survival in epithelial ovarian cancer. However, as RAN is a small GTPase involved in two main biological functions, nucleo-cytoplasmic transport and mitosis, it is still unknown which of these functions as...

Journal: :Toxicological sciences : an official journal of the Society of Toxicology 2007
Francis F Tukov James P Luyendyk Patricia E Ganey Robert A Roth

Exposure to a nontoxic dose of bacterial lipopolysaccharide (LPS) increases the hepatotoxicity of the histamine-2 (H2) receptor antagonist, ranitidine (RAN). Because some of the pathophysiologic effects associated with LPS are mediated through the expression and release of inflammatory mediators such as tumor necrosis factor alpha (TNF), this study was designed to gain insights into the role of...

Journal: :Journal of Cell Biology 2002

Journal: :Molecular Biology of the Cell 2011

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