Radiotherapy interventions are rapidly evolving and improving, holding promise for better patient outcomes, yet at the possible detriment of higher societal costs. The ESTRO-HERO value-based radiotherapy project aims to develop a framework defining assessing value innovations, support clinical implementation equitable access, within sustainable healthcare system.

Background: Craniospinal radiotherapy faces technical challenges which are due to the sensitivity of the location in which the gross tumor is, and to organs at risk around planning target volume. Using modern treatment planning systems causes a reduction in the complexities of the treatment techniques. The most effective method to assess the dosimetric accuracy and the validity of the ...

Head and neck radiotherapy has some intraoral side effects that affect the treatment planning for oral rehabilitation .some treatment options have been discussed in articles. Choosing the best treatment should be based on the patient’s oral conditions affected by radiotherapy.  

Two quality control devices, light-field device and radiation-field device, have been specially designed to facilitate the clinical implementation of conformal dynamic arc treatment (CDAT) and intensity modulated radiation therapy (IMRT). With the devices, the light field as well as the radiation field, projected from the individual beam at any treatment position (i.e. arbitrary gantry angle) c...

BACKGROUND The optimal timing of salvage radiotherapy for biochemical recurrence after radical prostatectomy is controversial. In particular, the prognostic significance of salvage radiotherapy delivered before a current definition of biochemical recurrence, i.e. ultra-early salvage radiotherapy, is unclear. METHODS We reviewed 76 patients with pT2-3N0M0 prostate cancer who underwent salvage ...

BACKGROUND Glioblastoma, the most common primary brain tumor in adults, is usually rapidly fatal. The current standard of care for newly diagnosed glioblastoma is surgical resection to the extent feasible, followed by adjuvant radiotherapy. In this trial we compared radiotherapy alone with radiotherapy plus temozolomide, given concomitantly with and after radiotherapy, in terms of efficacy and ...

Introduction: Salivary gland cancer is an uncommon malignancy in the head and neck. The most common histopathologic type salivary malignancies mucoepidermoid carcinoma (MEC). Radiotherapy has a role malignancy, especially inoperable cases postoperative settings. Definitive or radiotherapy with without chemotherapy can improve locoregional control (LRC) patients parotid carcinoma. Case Presentat...

Importance Postoperative radiotherapy to the craniospinal axis is standard-of-care for pediatric medulloblastoma but is associated with long-term morbidity, particularly in young children. With the advent of modern adjuvant chemotherapy strategies, postoperative radiotherapy deferral has gained acceptance in children younger than 3 years, although it remains controversial in older children. O...

BACKGROUND The frequency and grade of pulmonary complications after radiotherapy for breast cancer are still debated. This study evaluated changes in pulmonary function tests (PFTs) after radiotherapy in women with breast cancer. PATIENTS AND METHODS Thirty-five consecutive eligible women with breast cancer underwent pulmonary function testing before and 3 months after adjuvant radiotherapy. ...