Identification of the individual radiosensitivity of workers exposed to ionising radiation is crucial for protecting these workers from the adverse health-and-safety effects of radiation. This study aims to test and vet a new cytogenetic biomarker called G2 assay, which assesses individual radiosensitivity of healthcare personnel in medical diagnosis and treatment using ionising radiation. Anot...

A mathematical model is developed which describes the dynamics of radiation-induced mortality of a non-homogeneous (in radiosensitivity) mammalian population. It relates statistical biometric functions with statistical and dynamic characteristics of a critical system in organism of specimens composing this population. The model involves two types of distributions, the normal and the log-normal,...

Currently, a linear no-threshold model is used to estimate health risks associated with exposure to low-dose radiation, a prevalent exposure in the general population, because the direct estimation from epidemiological studies suffers from uncertainty. This model has been criticized based on unique biology of low-dose radiation. Whether the departure from linearity is toward increased or decrea...

Atomic radiations are a very diverse group of physical agents all of which, however, produce damage in living cells. The common property which links them is the ability to knock out electrons from the atoms and molecules through which they pass. This process, known as ionization, is the starting point of radiation injury. Mammalian cells are amongst the most sensitive of all living matter, and ...

Radiosensitivity is a term used to designate the reaction of cells to radiation, and the radiotherapy of malignant disease is based upon the difference in radiosensitivity between neoplastic cells and the normal cells which surround them. The factors that enter into radiosensitivity are many. The general condition of the patient often has a most important influence on the behavior of the tumor ...

Inside Back Cover In article number 2200570, Ma, Xu, and co-workers highlight the biophysical cue, a new hallmark of cancer, serving as significant factor in tumor microenvironment forming physical microenvironment, including extracellular matrix microarchitecture, stiffness, interstitial fluid pressure, solid stress. It plays an essential role affecting radiotherapy efficacy. Meanwhile, also a...