To develop and apply a remote dosimetry protocol with PRESAGE® radiochromic plastic and optical-CT readout in the validation of MRI guided radiation therapy (MRgRT) treatments (MRIdian® by ViewRay®). Through multi-institutional collaboration we performed PRESAGE® dosimetry studies in 4ml cuvettes to investigate dose-response linearity, MRcompatibility, and energy-independence. An open calibrati...

background: the goals of the present research were to investigate the rectal dose during four chosen techniques of cervical cancer radiotherapy and to examine how accurately the treatment planning represents dose measurements, and it’s practicality for routine use as well as, to determine the homogeneity of dose in tumor volume. materials and methods: the study was carried out using a nepton 10...

Commercially available radiochromic films are primarily designed for clinical X-ray dosimetry. These films change color upon exposures to radiation as a result of solid-state polymerization (SSP). Built on a previous model developed for SSP upon exposures to ultraviolet (UV) radiation, a new model was developed in the present work for X-ray-induced coloration in Gafchromic EBT3 films. Monte Car...

PURPOSE Bombarding high-Z material with x-ray radiation releases Auger electrons and Coster-Kronig electrons, along with deeper penetrating fluorescent x-rays and photoelectrons. The Auger and Coster-Kronig electron penetration distance is on the order of nanometers to micrometers in water or tissue, creating a large dose enhancement accompanied by a RBE greater than 1 at the cellular level. Th...

PURPOSE Sophisticated small animal irradiators, incorporating cone-beam-CT image-guidance, have recently been developed which enable exploration of the efficacy of advanced radiation treatments in the preclinical setting. Microstereotactic-body-radiation-therapy (microSBRT) is one technique of interest, utilizing field sizes in the range of 1-15 mm. Verification of the accuracy of microSBRT tre...

max. 2000 char.): A comparison of dosimetry methods at different clinics can be used as a means to uncover systematic uncertainties in radiotherapy. To assess the current status of reference dosimetry and small-field dosimetry in clinical practice, a collaborative comparison study involving several dosimetry methods was performed by DTU Nutech at six Danish clinics. The first part of the interc...

Abstract In vivo dosimetry for patient radioprotection is a real challenge concerning new radiotherapy treatments. this study we aim to develop dosimeter based on tissue equivalent material, flexible and adaptable the morphology in order perform complex irradiation beams. Here, report evaluation standard beams of highly composed silicone elastomer containing leucomalachite green as radiochromic...