Surgery is excellent therapy for hyperthyroidism, with no mortality,and few complications or recurrences. It achieves euthyroidism rapidly and consistently, avoids long-term risks of radioactive iodine and antithyroid medications, provides tissue for histology,renders childbearing immediately possible, and allows absolute titration of thyroid hormone. Advancements such as preoperative preparati...

Two middle aged Caucasian women with no previous history of thyroid or any other disease developed typical subacute thyroiditis (SAT) with minimal thyroidal radioactive iodine uptake. A few months after restoration of euthyroidism and discontinuation of corticosteroid therapy, they developed mild hyperthyroidism due to Graves’ disease (GD), as judged by the increased diffuse thyroidal radioacti...

BACKGROUND In well-differentiated thyroid carcinoma, predictors of future positivity of stimulated thyroglobulin (>2 microg/L) after initial radioactive iodine treatment are not known. METHODS In a retrospective study, we used logistic regression analysis to determine whether postoperative stimulated thyroglobulin measurements and pathologic stage independently predict future stimulated thyro...

The Treatment Paradigm (Figure 1) Methimazole (MMI) was started 3 to 6 months before 131I therapy to restore euthyroidism and was discontinued 5 days (T-5) before 131I was initiated. On the same day, lithium, 900 mg/day was started. Seven days after 131I was administered (day T0), lithium was withdrawn, comprising 12 days of lithium, and oral prednisone was started at 0.5 mg/kg daily to avoid 1...

Hyperthyroidism is recognized as the most common endocrinopathy of older cats. Despite worldwide occurrence, the pathogenesis of feline hyperthyroidism remains unclear. Traditional methods of managing feline hyperthyroidism include thyroidectomy, anti-thyroid medications, and radioactive iodine. Recent studies document that another option now exists for hyperthyroid cats; feeding a limitediodin...

We present the case of a 57-year-old woman diagnosed with breast cancer and a thyroid mass that was suspicious for cancer. The breast cancer was estrogen and progesterone receptor negative, HER2/neu borderline, with a high proliferative index. Treatment of this cancer took precedence. Nine months later, a total thyroidectomy was done for papillary thyroid cancer with metastases to 2 of 8 perith...

Enlargement of the thyroid gland is an unusual finding in cretins outside endemic goitrous areas. Wilkins, Clayton and Bertirong (1954), reviewing published cases of non-endemic goitrous cretinism, collected reports of 32 cases and described a further four cases of their own. Other cases have been reported by Rienhoff (1940) and Smallpeice (1949). The hypothyroidism in these cases is of variabl...

Hyperthyroidism is an excessive concentration of thyroid hormones in tissues caused by increased synthesis of thyroid hormones, excessive release of preformed thyroid hormones, or an endogenous or exogenous extrathyroidal source. The most common causes of an excessive production of thyroid hormones are Graves disease, toxic multinodular goiter, and toxic adenoma. The most common cause of an exc...

The current literature on radionuclide therapy is heavily based on health care professionals' perspectives and provides little insight regarding what patients or family members identify as their needs or concerns. Family members (N = 130) of patients undergoing treatment with radioactive iodine were selected from eight programs across Canada to participate in a survey to identify the needs they...