INTRODUCTION The angular dependency of response for TLD cards may cause deviation from its true value on the results of environmental dosimetry, since TLDs may be exposed to radiation at different angles of incidence from the surrounding area. OBJECTIVE A 3D setting of TLD cards has been calibrated isotropically in a standard radiation field to evaluate the improvement of the accuracy of meas...

Biological dosimetry, based on the analysis of dicentric chromosomes, is an internationally established, independent method applied in the area of radiation protection. The biodosimetry is mainly performed, in addition to physical dosimetry, with the aim of individual dose assessment, especially after unclear or suspected radiation dose exposures. However, a new biodosimetrical challenge has em...

INTRODUCTION Radiotherapy is a common treatment modality for patients with head and neck malignancies. As the nose lies within the field of radiotherapy of the head and neck, the olfactory fibers and olfactory receptors may be affected by radiation. The aim of this study was to evaluate changes in olfactory threshold in patients with head and neck malignancies who have received radiation to the...

When Policy Topic is covered Intensity-modulated radiation therapy (IMRT) may be considered medically necessary as a technique to deliver whole breast irradiation in patients receiving treatment for left-sided breast cancer after breast-conserving surgery when all the following conditions have been met:  Significant cardiac radiation exposure cannot be avoided using alternative radiation techn...

Dosimetry based on the detection by electron paramagnetic resonance (EPR) spectroscopy of ionizing radiation-induced radicals is an established method for the retrospective dosimetry of past exposures and the dosimetry of potentially exposed persons in radiological emergencies. The dose is estimated by measuring the physical damage induced in materials contained in objects placed on or next to ...

The purpose of this study was to ensure accuracy in radiation dose delivery, external dosimetry quality audit has an equal importance with routine dosimetry performed at clinics. To do so, dosimetry quality audit was organized by the Secondary Standard Dosimetry Laboratory (SSDL) of Pakistan Institute of Nuclear Science and Technology (PINSTECH) at the national level to investigate and minimize...

BACKGROUND Features of the tumor microenvironment influence the efficacy of cancer nanotherapeutics. The ability to directly radiolabel nanotherapeutics offers a valuable translational tool to obtain biodistribution and tumor deposition data, testing the hypothesis that the extent of delivery predicts therapeutic outcome. In support of a first in-human clinical trial with (64)Cu-labeled HER2-ta...

Introduction: Currently, the potential application of gold nanoparticles (AuNPs) to increase the efficiency of radiation therapy have been investigated. However, the loss of an appropriate method to estimate the dose distribution in nanoparticle laden tissue limits the applicability of nanoparticles in radiotherapy clinics. Polymer gel dosimetry provides an accurate and precise...