Objective To investigate the phenotypic relationships between aortic stiffness and left ventricular (LV) stroke volume (SV) and modes of deformation (longitudinal LD and radial -RD) at rest and stress, with preserved and compromised contractile capacity. Background Increased aortic stiffness, measured by pulse wave velocity (PWV), is linked to a range of cardiovascular (CV) risk factors and act...

In this paper the authors derive a higher-order shear deformation theory for modelling functionally graded plates accounting for extensibility in the thickness direction. The explicit governing equations and boundary conditions are obtained using the principle of virtual displacements under Carrera’s Unified Formulation and then interpolated by collocation with radial basis functions. The effic...

Background Quantitative MR myocardial strain analysis is typically performed using rectilinear or Cartesian grid tagging, and regional contractility is visually assessed by the deformation of the grid1. However, it is difficult to visually isolate circumferential and radial components of displacement and strain from parallel straight lines on short axis images. This study evaluates the potentia...

Magnetic resonance tissue tagging allows noninvasive in vivo measurement of soft tissue deformation. Planes of magnetic saturation are created, orthogonal to the imaging plane, which form dark lines (stripes) in the image. The authors describe a method for tracking stripe motion in the image plane, and show how this information can be incorporated into a finite element model of the underlying d...

Two-dimensional speckle tracking echocardiography (2DSTE) offers valuable information in the echocardiographic assessment of ventricular myocardial function. It enables the quantification and timing of systolic ventricular myocardial deformation. In addition, 2DSTE can be used to identify mechanical dyssynchrony, which is an important parameter in predicting the response to cardiac resynchroniz...

Brush seals can improve engine performance by reducing leakage. Wear models of brush provide methods to predict wear and However, rotor eccentricity, radial deformation, hysteresis effect bristles are not considered systematically in the existing models, which may lead large errors some cases. To investigate influence rotor-stator eccentricity deformation on process leakage seal, a seal test wa...

Edaravone, an effective free radical scavenger, can alleviate myocardial ischemia-reperfusion injury (IRI) by decreasing reactive oxygen species (ROS) accumulation. The speckle tracking imaging (STI) could precisely and objectively evaluate the global and regional myocardial deformation. The aim of our study was to assess the protective effect of edaravone postconditioning on IRI in rabbits by ...