BACKGROUND Aspirin is effective for the primary prevention of cardiovascular events, but it remains unclear for which subgroups of individuals aspirin is beneficial. We assessed the cost-effectiveness of aspirin separately for men and women of different ages with various levels of cardiovascular disease risk. METHODS AND RESULTS A Markov model was developed to predict the number of cardiovasc...

Abstract Background The payment card (PC) format and the open-ended (OE) are common methods in eliciting willingness-to-pay (WTP) of one additional quality-adjusted life year (QALY). aim this research is to compare these two formats monetary value a QALY. Methods A contingent valuation survey was carried out using pre-designed questionnaire with various hypothetical scenarios. difference betwee...

BACKGROUND The International Carotid Stenting Study was a multicenter randomized trial in which patients with symptomatic carotid artery stenosis were randomly allocated to treatment by carotid stenting or endarterectomy. Economic evidence comparing these treatments is limited and inconsistent. AIMS We compared the cost-effectiveness of stenting versus endarterectomy using International Carot...

OBJECTIVES To investigate the cost-effectiveness of a telehealthcare solution in addition to usual care compared with usual care. DESIGN A 12-month cost-utility analysis conducted alongside a cluster-randomised trial. SETTING Community-based setting in the geographical area of North Denmark Region in Denmark. PARTICIPANTS 26 municipality districts define randomisation clusters with 13 dis...

PURPOSE To evaluate the cost-effectiveness of interferon alfa (IFN alpha) treatment of patients with chronic myelogenous leukemia relative to conventional chemotherapy. MATERIALS AND METHODS A decision-analysis model that involved a multistate Markov process was designed to estimate the expected cost and quality-adjusted life expectancies for two cohorts of patients to be administered convent...

The value of measuring the population burden of fatal and nonfatal injury is well established. Population health metrics are important for assessing health status and health-related quality of life after injury and for integrating mortality, disability, and quality-of-life consequences. A frequently used population health metric is the disability-adjusted life-year. This metric was launched in ...