A fully automatic mesher has been developed which is capable of generating both quadrilateral and triangular elements in 2-D and on surfaces using the advancing front algorithm. This allows the formation of meshes which range from being all-quad or nearly all-quad down to all-triangular. In mixed-element meshes, the number of tri elements present is dictated by the maximum allowable level of qu...

The efficient, computer aided or automatic generation of quad layouts, i.e. the partitioning of an object’s surface into simple networks of conforming quadrilateral patches, is a task that – despite its importance and utility in Computer Graphics and Geometric Modeling – received relatively low attention in the past. As a consequence, this task is most often performed manually by well-trained e...

RNase H1 from Halobacterium sp. NRC-1 (Halo-RNase H1) is characterized by the abundance of acidic residues on the surface, including bi/quad-aspartate site residues. Halo-RNase H1 exists in partially folded (I) and native (N) states in low-salt and high-salt conditions respectively. Its folding is also induced by divalent metal ions. To understand this unique folding mechanism of Halo-RNase H1,...

We have fabricated sub-millimeter-sized quad corner-cube retroreflectors (CCRs) for free-space optical communication. Each quad CCR structure comprises three mirrors micromachined from silicon-on-insulator wafers, and is designed to facilitate manual assembly with accurate angular alignment. Assembled CCRs exhibit mirror nonflatness less than 50 nm, mirror roughness less than 2 nm, and mirror m...

Presented here is a slotted-quad-beam structure sensor for the measurement of friction in micro bearings. Stress concentration slots are incorporated into a conventional quad-beam structure to improve the sensitivity of force measurements. The performance comparison between the quad-beam structure sensor and the slotted-quad-beam structure sensor are performed by theoretical modeling and finite...

The quad pill is the newest single-pill, once-daily option for the treatment of human immunodeficiency virus (HIV) type 1 infection. In addition to tenofovir difumarate (TDF) and emtricitabine (FTC), the quad pill includes cobicistat (COBI; an inactivator of cytochrome P450 isoenzyme CYP3A without anti-HIV activity) and a new integrase inhibitor, elvitegravir (EVG). The quad does not have drug ...

This short note regards a comparison of instantaneous power, total energy consumption, execution time and energetic cost per synaptic event of a spiking neural network simulator (DPSNN-STDP) distributed on MPI processes when executed either on an embedded platform (based on a dual-socket quad-core ARM platform) or a server platform (INTELbased quad-core dual-socket platform). We also compare th...

In this work we present an initial performance evaluation of Intel's latest, secondgeneration quad-core processor, Nehalem, and provide a comparison to first-generation AMD and Intel quad-core processors Barcelona and Tigerton. Nehalem is the first Intel processor to implement a NUMA architecture incorporating QuickPath Interconnect for interconnecting processors within a node, and the first to...

Glioblastoma (GBM) is among the most invasive and lethal of cancers, frequently infiltrating surrounding healthy tissue and giving rise to rapid recurrence. It is therefore critical to establish experimental model systems and develop therapeutic approaches that enhance anti-tumor immunity. In the current study, we have employed a newly developed murine glioma model to assess the efficacy of a n...