Pulmonary vein isolation(PVI) is less effective in patients with persistent atrial fibrillation(PsAF). Adjunctive ablation targeting low voltage areas(LVA) had demonstrated improved arrhythmia outcomes. To compare the outcomes of adding posterior wall isolation(PWI) to PVI, versus PVI alone, PsAF LVA. The CAPLA study was a multi-centre, randomized trial involving 1:1 either alone or PWI. Voltag...

PURPOSE Crossed cerebellar diaschisis (CCD) is a state of neural depression caused by loss of connections to injured neural structures remote from the cerebellum usually evaluated by positron emission tomography. Recently it has been shown that dynamic susceptibility contrast perfusion weighted MRI (PWI) may also be feasible to detect the phenomenon. In this study we aimed to assess the frequen...

The abdominal aortic aneurysm (AAA) is a silent and often deadly vascular disease caused by the localized weakening of the arterial wall. Previous work has indicated that local changes in wall stiffness can be detected with pulse wave imaging (PWI), which is a non-invasive technique for tracking the propagation of pulse waves along the aorta at high spatial and temporal resolutions. The aim of ...

An accurate characterization of glioma heterogeneity is essential when determining tumor grade and the most appropriate therapy target. Non-invasive imaging modalities such as MR perfusion imaging (PWI) and 2D proton MR spectroscopic imaging (MRSI) can provide functional and metabolic information about the tumor to assist in this task. Using a voxel-wise correlation we aimed at investigating wh...

The Distractor Frequency Effect in Stroop and Picture-word Interference Paradigms by Jingyi Geng The color naming (Stroop) and picture-word interference (PWI) paradigms play a pivotal role in theorizing about cognitive processes in general, and language production in particular. Despite their assumed similarities, there exist discrepancies. In this study, I compared the effect of distractor wor...

OBJECTIVE Having a good quality of life has always been desirable for humans and the concept of a good life and the ways of achieving it have been focused over the years. Personal wellbeing is the mental component of quality of life. Thus, the current study was conducted to estimate psychometric characteristics of "personal well-being index-adult" (PWI-A) in mothers of mentally retarded student...

BACKGROUND AND PURPOSE The pathophysiology of borderzone infarcts is not well understood. We investigated whether combined diffusion-weighted imaging (DWI) and perfusion-weighted imaging (PWI) could identify pathophysiologically meaningful categories of borderzone infarcts. METHODS Seventeen patients with borderzone infarcts were identified from the Beth Israel Deaconess Medical Center Stroke...

Pulse wave imaging (PWI) is an ultrasound-based method for noninvasive characterization of arterial stiffness based on pulse wave propagation. Reliable numerical models of pulse wave propagation in normal and pathological aortas could serve as powerful tools for local pulse wave analysis and a guideline for PWI measurements in vivo. The objectives of this paper are to (1) apply a fluid-structur...

BACKGROUND AND PURPOSE Hyperperfusion syndrome (HS) after carotid endarterectomy (CEA) has been related to impaired cerebrovascular autoregulation in a chronically hypoperfused hemisphere. Our aim was to provide new insight into the pathophysiology of the HS using magnetic resonance imaging (MRI) studies with diffusion-weighted imaging (DWI) and perfusion-weighted imaging (PWI). METHODS Five ...

BACKGROUND Effective therapy was not available for treatment of acute stroke until 1995, when tissue plasminogen activator (tPA) was shown to improve neurological and functional outcome in stroke patients who were treated within 3 hours of symptom onset. SUMMARY OF REVIEW Currently, many patients do not qualify for tPA therapy because they present for evaluation beyond 3 hours after stroke on...