PURPOSE We set out to determine whether individuals with central field loss benefit from using two eyes to perform a grasping task. Specifically, we tested the hypothesis that this advantage is correlated with coarse stereopsis, in addition to binocular summation indices of visual acuity, contrast sensitivity, and binocular visual field. METHODS Sixteen participants with macular degeneration ...

OBJECTIVES We hypothesized that integrated motor-visual functions measured by manipulative manual dexterity are affected by white matter lesion (WML) burden as measured on cranial MRI across relevant brain regions in subjects at risk of preclinical occult vascular disease. METHODS A real-time cross-sectional study of healthy subjects aged 29 to 74 years with a family history of early-onset co...

Any task is carried out more successfully if we allocate undivided attention to it, but as demands on attentional capacity increase-for example, in concurrent or dual task conditions-performance on attended tasks becomes more impaired. Patients with schizophrenia show impaired performance on tasks requiring high levels of attentional capacity. This study examines performance of 11 patients with...

BACKGROUND AND PURPOSE Developing a better understanding of the trajectory and timing of stroke recovery is critical for developing patient-centered rehabilitation approaches. Here, we quantified proprioceptive and motor deficits using robotic technology during the first 6 months post stroke to characterize timing and patterns in recovery. We also make comparisons of robotic assessments to trad...

Dopamine depletion in the putamen is associated with altered motor network functional connectivity in people with Parkinson's disease (PD), but the functional significance of these changes remains unclear, attributed to either pathological or compensatory mechanisms in different studies. Here, we examined the effects of PD on dorsal caudal putamen functional connectivity, off and on dopamine re...

OBJECTIVES Antidepressants, among the most commonly prescribed medications, trigger symptoms of REM sleep behavior disorder (RBD) in up to 6% of users. Idiopathic RBD is a very strong prodromal marker of Parkinson disease and other synuclein-mediated neurodegenerative syndromes. It is therefore critically important to understand whether antidepressant-associated RBD is an independent pharmacolo...

BACKGROUND AND PURPOSE The sequence effect (SE) in Parkinson's disease (PD) denotes progressive slowness in speed or progressive decrease in amplitude of repetitive movements. It is a well-known feature of bradykinesia and is considered unique in PD. Until now, it was well-documented in advanced PD, but not in drug-naïve PD. The aim of this study is to know whether the SE can also be measured i...

Upper limb movements such as using chopsticks and writing require coordination. Hence, coordination tests such as the Purdue Pegboard test (Buddenberg & Davis, 2000) and the Moving Beans with Tweezers test (Shigematsu et al., 2001) have been developed (Ferslew et al., 1982; Noguchi et al., 2006; Nakafuji & Tsuji, 2001). Nagasawa et al. (2002) developed a controlled force exertion (CFE) test pur...

Abstract Objective As neuropsychologists adopt virtual assessments in the context of COVID-19, field is shifting toward teleneuropsychology. Comprehensive remote evaluations are proving to be feasible and reliable across domains, though traditional fine motor (FM) tests cannot administered virtually. In absence direct FM measurement, this cross-sectional study considered whether universal recom...