Coronary artery bypass grafting: on-pump or off-pump? With a growing evidence base surrounding off-pump cardiac surgery, Confluence spoke to Professor Massimo G Lemma, Luigi Sacco University General Hospital, Milan, Italy about how the results of his most recent study investigating on-pump versus off-pump coronary artery bypass surgery in high-risk patients might impact clinical practice. m g L...

We compared stroke rates associated with coronary artery bypass grafting (CABG), both on-pump and off-pump, and percutaneous coronary intervention (PCI) with both drug-eluting stent (DES) and bare-metal stent (BMS) and the impact on 30-day and 1-year all-cause mortality. The Myocardial Infarction Data Acquisition System database was used to study patients who had on-pump CABG (n = 47,254), off-...

An infusion pump powered by body heat is investigated in this paper, with the goal of addressing the needs of dermal wound healing. The infusion pump incorporates a Knudsen gas pump, a type of thermally driven pump, to pneumatic push the pharmaceutical agent from a reservoir. Two designs are considered: an integrated pump and reservoir, and a design with cascaded pump and reservoir. Thermal mod...

Background—The Department of Veterans Affairs Randomized On/Off Bypass (ROOBY) trial compared clinical and angiographic outcomes in off-pump versus on-pump coronary artery bypass graft (CABG) surgery to ascertain the relative efficacy of the 2 techniques. Methods and Results—From February 2002 to May 2007, the ROOBY trial randomized 2203 patients to off-pump versus on-pump CABG. Follow-up angio...

OBJECTIVE Postoperative vasoplegic syndrome (PVS) is a potentially lethal condition with increased mortality and other postoperative morbidities. Many previous studies have examined the outcomes associated with on-pump coronary artery bypass grafting (CABG) surgery, little is known about the incidence of PVS after off-pump CABG. METHODS From November 21, 2005 to June 9, 2006, 334 patients und...

BACKGROUND Coronary endarterectomy (CE) is an alternative for the diffusely diseased left anterior descending (LAD), but its mid and long term results are largely questionable. This study is to compare the early to mid-term results between off-pump and on-pump coronary endarterectomy with coronary artery bypass grafting. METHODS 212 consecutive patients underwent CE and bypass grafting for di...

BACKGROUND The Department of Veterans Affairs Randomized On/Off Bypass (ROOBY) trial compared clinical and angiographic outcomes in off-pump versus on-pump coronary artery bypass graft (CABG) surgery to ascertain the relative efficacy of the 2 techniques. METHODS AND RESULTS From February 2002 to May 2007, the ROOBY trial randomized 2203 patients to off-pump versus on-pump CABG. Follow-up ang...

background: there are some conflicting results with conventional coronary artery bypass grafts (ccabg) with arrested heart in coronary high-risk patients. moreover, performing off-pump cabg in these cases may be associated with serious complications. the objective of this study is to evaluate the efficacy of the on-pump beating cabg (opbcabg) in coronary high-risk patients in comparison with th...

background: liver dysfunction during on-pump coronary artery bypass graft surgery (cabg) is a rare complication but is associated with significant morbidity and mortality. the ability to identify high-risk patients may be helpful in planning appropriate management strategies. we aimed to evaluate the factors influencing liver function tests during on-pump cabg. methods: in 146 patients schedule...

background: acinetobacter baumannii is an important human pathogen with increasing notoriety in the recent years, as a causative organism of drug resistant nosocomial infections, particularly in immunocompromised patients hospitalized in burn centers. objectives: the aim of this study was to determinate the role of efflux pump(s) in ciprofloxacin resistance of a. baumannii strains isolated from...