objective rubinstein-taybi syndrome is a rare genetic disorder with characteristic featuresincluding downward slanting palpebral fissures, broad thumbs and halluces,and mental retardation. systemic features may involve cardiac, auditory,ophthalmic, endocrine, nervous, renal and respiratory systems. this syndromeis sporadic in nature and has been linked to microdeletion at 16p 13.3 encodingcreb-...

The purpose of this study was to explore the effective prevention and control method ground fissures in plain coal mining subsidence. Firstly, model experiment carried out, then two typical working faces, face A (WFA) B (WFB), Huaibei area were selected for case moisturization method. Model experimental results show that water content had a significant effect on cohesive soil fissure developmen...

emergency centre staffed with GPs, nurse practitioners, and emergency medicine doctors. Handover between OOH and in-hours GPs has been defined as ‘one of the most perilous procedures in medicine, and when carried out improperly can be a major contributory factor to subsequent error and harm to patients’.1 In-hours care accounts for 50 hours/week while OOH care accounts for 118 hours/week. Hando...

pulmonary arteriovenous malformations are rare clinical entities thai are associated with right to left shunts, and are often clinically presented by the triad of dyspnea, cyanosis, and digital clubbing. currently, transcatheter embolization of fistula is gaining increasing popularity as the superior therapeutic option. in certain situations, however, surgery is preferred. two cases of direct p...

Early anatomists referred to parts of the brain as 'posterior' and 'anterior.' But after comparing many primate brains, Gratiolet noticed a pattern of folds or sulci and convolutions marked by fissures of increasing complexity in the more advanced mammalian brains. The primary fissures he could also identify in the smoother ape brains. He was the first to separate four brain lobes (frontal, par...

Anal fissures are common in infancy and represent the most common cause of bright rectal bleeding at any age. Delayed diagnosis and treatment can lead to a disturbing cycle of constipation, repeat rectal bleeding, and crying, due to increasing pain during and after defecation. In spite of its high frequency, the problem remains underrated by most clinicians, with only a paucity of data on the m...

Chronic obstructive pulmonary disease (COPD) is characterized by two entities, the more airway-predominant type (“bronchitis”) on the one hand, and emphysema-predominant type on the other. Imaging via high-resolution computed tomography plays an important role in phenotyping COPD. For patients with advanced lung emphysema, new endoscopic lung volume reduction therapies (ELVR) have been develope...