The extracellular enzymatic hydrolysis rates of three fluorescently-labeled polysaccharides (pullulan, laminarin, and xylan) were measured in the upper -11 cm of sediment cores collected near Svalbard in the Arctic Ocean. The three polysaccharides differ in molecular weight (200,000, -6,000, and -8,000 Da for pullulan, laminarin, and xylan, respectively), as well as in monomer composition, link...

Glycyrrhetic acid (GA)-modified pullulan nanoparticles (GAP NPs) were synthesized as a novel carrier of curcumin (CUR) with a degree of substitution (DS) of GA moieties within the range of 1.2-6.2 groups per hundred glucose units. In the present study, we investigated the physicochemical characteristics, release behavior, in vitro cytotoxicity and cellular uptake of the particles. Self-assemble...

The molecular weight (MW) of heparin can be accurately determined by size exclusion chromatography using "universal calibration." A universal calibration curve was constructed for Superose 12 with standard pullulan samples and verified using characterized ficoll fractions. This calibration yielded the correct MW of heparin as determined by light scattering, when the ionic strength of the mobile...