Introduction In vivo proton magnetic resonance spectroscopy (H-MRS) has been used to measure metabolic changes in the brain of epilepsy patients. Significantly reduced NAA/total creatine (tCr) ratios have been observed in the hippocampus and/or thalamus of patients with temporal lobe epilepsy (TLE), indicative of neuronal dysfunction/loss in these regions [1]. Pentylenetetrazol (PTZ) is a GABAA...

Pengembangan penggunaan kamera PTZ masih terfokus pada tracking posisi obyek dan kalibrasi kamera. Kamera akan melakukan bergerak mengikuti pergerakan obyek. Namun ketika menjauhi kamera, ukuran mengecil sulit terdeteksi oleh Sehingga diperlukan perbesaran (zoom) untuk membesar Penggunaan fitur zoom saat ini dilakukan secara manual user. Penelitian bertujuan membangun sistem kontrol objek denga...

Tracking of moving objects in pan-tilt-zoom (PTZ) cameras is a critical feature for automated surveillance applications. The PTZ auto tracking function enables the camera to control its electric motor mechanisms adjust course optical sensor field view (FOV) track automatically. In this paper, proposed novel object method based on fusion thermal, and millimeter-wave data implemented. implementat...

The possible involvement of vasoactive intestinal polypeptide-related peptides in pentylenetetrazol (PTZ)-induced seizures in rats was investigated. The chemoconvulsant PTZ was administered (45 mg/kg i.p.) either acutely or chronically for three days. The detailed time course of changes in VIP-(1-28) and VIP-(22-28) was examined in several rat brain areas 5 and 20 min and 24 h after acute treat...

BACKGROUND The polysialylated neural cell adhesion molecule (PSA-NCAM) is expressed in developing brain. Fetal brain damage is caused by different conditions such as seizure and hypoxia. The present study was designed to investigate the effect of maternal seizures on the number of PSA-NCAM positive cells in pup's hippocampus. METHODS Female Wistar rats were divided into four groups: (a) kindl...

The chloroform (4.20% w/w), ethyl acetate (4.23% w/w) and aqueous decoction (12.11% w/w) extracts of the aerial parts of A. indica were screened for the antiepileptic activity against maximal electroshock (MES) model and pentylenetetrazole (PTZ) models at doses of 200, 400 mg/kg, po once. Phenytoin and diazepam (25 and 2 mg/kg, ip) were used as standard drugs in MES and PTZ model, respectively....

Objective: Antiepileptic drugs (AEDs) that are usually used for treatment of epilepsy have substantial side effects and about 30% of patients continue to have seizures with current AEDs therapy. Some herbs which traditionally used in the management of seizures of many rural areas of the developing countries have shown anticonvulsant activity in modern pharmacological bioassays. The aim of the p...

The effect of pretreatment with essential oils (EOs) from eight aromatic plants on the seizure latency and severity of pentylenetetrazol- (PTZ-) induced seizures in mice was evaluated. Weight-dependent doses of Rosmarinus officinalis, Ocimum basilicum, Mentha spicata, Mentha pulegium, Lavandula angustifolia, Mentha piperita, Origanum dictamnus, and Origanum vulgare, isolated from the respective...

Temporal lobe epilepsy (TLE) is a disorder of the central nervous system in which hippocampus is mostly involved and causes memory impairment. Kindling is a model of inducing epilepsy which is created through pentylenetetrazol (PTZ) administration. This study examines the role of the aqueous extract of Boswellia on the learning and development of brain (formation of dendritic branches and axons...

Epilepsy is a chronic neurological disease which is usually associated with psychiatric comorbidities. Depsression and cognition impairment are considered to be the most common psychiatric comorbidities in epilepsy patients. However, the specific contribution of epilepsy made to these psychiatric comorbidities remains largely unknown. Here we use pentylenetetrazole (PTZ) kindling, a chronic epi...