Weaning is associated with a break in the mother-infant contact. In sheep, under natural conditions, the rupture of the social bond is progressive. In contrast, weaning imposed by breeders may result in psychobiological disturbances. The aim of this experiment was to measure the behavioural, hormonal and immune consequences of two types of sudden weaning: total separation (TS) and partial separ...

A chronic exposure to stress has been associated with neuroendocrine changes and metabolic disorders including obesity, glucose intolerance and insulin resistance. While these disorders have been identified as underlying causes in the development of pre-diabetes, the extent to which chronic psychological stress might represent a causal factor for the etiology of type2 diabetes has not been well...

The term premenstrual syndrome (PMS) has been used for many years to describe disturbances of mood or physical symptoms occurring regularly 7–10 days before menses and remitting during menses. The Diagnostic and Statistical Manual of Mental Disorders (DSM III-R) included PMS among the ‘proposed Diagnostic Categories Needing Further Study’ under the name of Late Luteal Phase Dysphoric Disorder (...

Experimental animal models have demonstrated that one of the primary consequences of prenatal stress is increased fear and anxiety in the offspring. Few prospective human studies have evaluated the consequences of prenatal stress on anxiety during preadolescence. The purpose of this investigation is to determine the consequences of prenatal exposure to both maternal biological stress signals an...

Individuals inherit not just genes from the parents but also an epigenetic pattern, an ecological (social, biological, and physical) niche, and perceptual and behavioral biases (e.g., culture), all of which can provide experiences necessary for the formation of nascent systems upon which subsequent learning and development depend. Some models of development are evaluated and the developmental p...

1. Preparing Institution: Institute for Behavioral Research, Inc. 2. Title of Report: The Psychobiological Investigation of the Development of New Verbal Behavior 3. Principal Investigator: C. B. Ferster 4. Number of pages, illustrations and date: 79; Figures 1-4; Tables 1-3; July 8, 1966 5. Contract Number: DA 49-193-ND-2577 6. Supported by: U. S. Army Medical Research and Development Command ...

Psychological studies in general, and psychobiological studies in particular, routinely use a collection of classic statistical techniques aimed at comparing groups or studying associations. A fundamental issue is whether violating the basic assumptions underlying these methods, namely normality and homoscedasticity, can result in relatively poor power or miss important features of the data tha...

Personality interacts with psychosocial variables, psychopathology and coping strategies of patients with schizophrenia. Psychobiological model of personality is important for schizophrenia as temperament dimensions, except dimension Persistence, have been associated with different neurotransmitter systems. Comorbidity of psychiatric and somatic disorders and syndromes is generally associated w...