A total synthesis of the cyanobacterial natural product nostodione A is reported involving a convergent, diversity-oriented route. A small assemblage of structural analogues were prepared and their cytotoxicity and anti-invasion activity against the protozoal parasite Toxoplasma gondii is reported for the first time.

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in this experiment, different doses of zataria multiflora (zm) and eucalyptus globolus (eg) essential oils (eos) (0, 100, 250, 500, 750 and 1000 µg/ml) and a mixture of them were added to alfalfa hay incubated with buffered rumen liquor of merghoz goat to assess in vitro gas production, rumen fermentation and protozoa population. in all treatments the asymptotic gas volume (b) and the rate cons...

We report a fatal case of disseminated strongyloidiasis in a patient with multiple myeloma receiving chemrotherapy. A fifty-seven years old man presented with severe diarrhoea and vomiting, fever, weight loss and dysphagia,due to mouth ulcers. Despite broad-spectrum intravenous antibiotics, albendazole (anti protozoal) and supportive treatment, the patient died of Gram-negative sepsis.

Sub-acute ruminal acidosis (SARA) is a gastrointestinal functional disorder in livestock characterized by low rumen pH, which reduces rumen function, microbial diversity, host performance, and host immune function. Dietary management is used to prevent SARA, often with yeast supplementation as a pH buffer. Almost nothing is known about the effect of SARA or yeast supplementation on ruminal prot...

The important viral, protozoal and bacterial diseases of wild African ruminants are reviewed. Special attention is paid to the epidemiological factors that determine the role played by these animals in the transmission of diseases to domestic stock. Examples of the converse situation where livestock serve as a source of infection for wild ruminants are also given.

Sulphonamides are the first effective chemotherapeutic agents used for bacterial infection in humans. Sulfonamides have a wide range of pharmacological activities such as Oral hypoglycemic, antileprotic, anti epileptic, anti-hypertensive, anti-bacterial, anti-protozoal, anti-fungal, anti retroviral, anti cancer, antiinflammatory, and used as diuretic. This review consists of a discussion on the...