Introduction: Proton therapy is a type of radiation treatment that it uses protons to treat cancer. Because of the protons’ unique ability to distribute the radiation dose more directly to the tumor, it minimizes the damage to nearby healthy tissues. The rate of energy loss by the ion in the target is called stopping power. The total stopping power is sum nuclear and electroni...

The University Proton Therapy facility in Dresden (UPTD), Germany, is equipped with an experimental room a beamline providing static pencil beam. High proton beam currents can be achieved at this which makes it suitable for FLASH experiments. However, the established setup uses only entrance channel of Bragg curve. In work, set 3D-printed range modulators designed to generate spread out peaks (...

Introduction Proton therapy is used to treat malignant tumors such as melanoma inside the eye. Proton particles are adjusted according to various parameters such as tumor size and position and patient’s distance from the proton source. The purpose of this study was to assess absorbed doses in eyes and various tumors found in the area of sclera and choroid and the adjacent tissues in radiotherap...

A therapy-dedicated cyclotron was installed in the National Cancer Center Hospital East (NCCHE) at Kashiwa in 1997. Prior to the start of clinical use, we investigated the biological effectiveness of therapeutic proton beams for cell lethality. The proton beams accelerated up to 235 MeV were horizontally extracted from the cyclotron, and scattered by a bar-ridge filter to produce a Spread-Out-B...

PURPOSE To obtain and assess the accuracy of 3D dose distributions and LET maps from a passively-scattered proton beam through the use of LET-dependent and LET-independent polymer gel formulations. METHODS Dose measurements were performed with BANG3-Pro2 (MGS Research, Inc, Madison, CT) polymer gel dosimeters. The dosimeters were mixed from kits and were poured into 14.5 cm high by 15 cm diam...

Ultrasound injection effect on a magnetic Bragg peak of yttrium iron garnet has been studied by quasielastic neutron scattering. The is vastly enhanced with decreasing temperature. energy width increases proportionally to the square root sample temperature increase induced ultrasound injection. Based liquid model, estimated effective mass becomes light when domain walls are removed under field....

Abstract The acoustic pulse emitted from the Bragg peak of a laser-accelerated proton bunch focused into water has recently enabled reconstruction energy distribution. By adding three ultrasonic transducers and implementing fast data analysis filtered raw signals, I-BEAT (Ion-Bunch Energy Acoustic Tracing) 3D now provides mean absolute lateral position in real-time for individual bunches. Relat...

Following the promising results of [1], further phantom experiments have been performed at GSI in order to address the feasibility and accuracy of in-beam positron emission tomography (PET) for proton therapy. For the most challenging issue of range monitoring it has been demonstrated for mono-energetic as well as for spread-out Bragg peak (SOBP) irradiation that range differences of about 0.9m...

The aim of this work was to model the characteristics of a clinical proton spot scanning beam using Monte Carlo simulations with the code MCNP6. The proton beam was defined using parameters obtained from beam commissioning at the Skandion Clinic, Uppsala, Sweden. Simulations were evaluated against measurements for proton energies between 60 and 226 MeV with regard to range in water, lateral spo...