نتایج جستجو برای: proteomics
تعداد نتایج: 30884 فیلتر نتایج به سال:
Enabling technologies for proteomics (studies examining the protein complement of the genome) have been in development for over 20 years. However, more recently, the field has become formalized by combining the techniques for large-scale protein separation (two-dimensional electrophoresis) with very precise, high fidelity approaches to the analysis and characterisation of the separated proteins...
pathological changes within an organ can be reflected as proteomic patterns in biological fluids such as plasma, serum, and urine. the surface-enhanced laser desorption and ionization time-of-flight mass spectrometry (seldi-tof ms) has been used to generate proteomic profiles from biological fluids. mass spectrometry yields redundant noisy data that the most data points are irrelevant features ...
This article represents the proceedings of a workshop at the 2003 annual meeting of the Research Society on Alcoholism in Fort Lauderdale, FL. The workshop organizers/chairpersons were Chinnaswamy Kasinathan and Paul Manowitz. The presentations were (1) Introduction to the field of proteomics, by Kent Vrana; (2) Use of proteomics in the identification of urinary biomarkers for alcohol intake, b...
Biomedical Knowledge of Proteomics Domain is represented in the Protein Ontology, whose instantiations, which are undergoing evolution, need a good management and maintenance system. Protein Ontology instantiations signify data and information about proteins that is shared and has evolved to reflect development in Protein Ontology Project and Proteomics Domain itself. Protein Ontology needs to ...
Identification of new biomarkers specific for various pathological conditions is an important field in medical sciences. Body fluids have emerging potential in biomarker studies especially those which are continuously available and can be collected by non-invasive means. Changes in the protein composition of body fluids such as tears, saliva, sweat, etc. may provide information on both local an...
Computational approaches have been major drivers behind the progress of proteomics in recent years. The aim of this white paper is to provide a framework for integrating computational proteomics into ELIXIR in the near future, and thus to broaden the portfolio of omics technologies supported by this European distributed infrastructure. This white paper is the direct result of a strategy meeting...
Proteomics studies typically aim to exhaustively detect peptides/proteins in a given biological sample. Over the past decade, the number of publications using proteomics methodologies has exploded. This was made possible due to the availability of high-quality genomic data and many technological advances in the fields of microfluidics and mass spectrometry. Proteomics in biomedical research was...
Proteomics is defined as the large-scale study of proteins, particularly their structures and functions. Clinical proteomics aims to apply proteomic discoveries and technologies to patient care. One of the workhorses of proteomics is mass spectrometry (MS). Over the last few years we have witnessed spectacular advances in MS-based proteomics; these advances now allow almost complete proteome id...
Proteomics as it is most commonly referred to is the study of the total complement of proteins in a closed system, the protein complement of the genome. Proteomics is a new kind of systems biology. Instead of studying one or more components of a system at a time, proteomics strives to study the whole system at once. Proteomics strives to do for proteins, what microarrays do for nucleic acids. P...
Microbial community proteomics, also termed metaproteomics, is an emerging field within the area of microbiology, which studies the entire protein complement recovered directly from a complex environmental microbial community at a given point in time. Although it is still in its infancy, microbial community proteomics has shown its powerful potential in exploring microbial diversity, metabolic ...
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