نتایج جستجو برای: protein protein interaction network analysis
تعداد نتایج: 4665176 فیلتر نتایج به سال:
Protein-protein interactions play a major role in most cellular processes. Thus, the challenge of identifying the full repertoire of interacting proteins in the cell is of great importance, and has been addressed both experimentally and computationally. Today, large scale experimental studies of interacting proteins, while partial and noisy, allow us to characterize properties of interacting pr...
AIM The aim of this study is to investigate the Protein-Protein Interaction Network of Celiac Disease. BACKGROUND Celiac disease (CD) is an autoimmune disease with susceptibility of individuals to gluten of wheat, rye and barley. Understanding the molecular mechanisms and involved pathway may lead to the development of drug target discovery. The protein interaction network is one of the suppo...
Proteins are linear polymers built from 20 building blocks called amino acids. Parts of a protein that are found conserved in many other proteins are called domains; these domains are usually responsible for the protein-protein interactions. Protein-protein interactions (PPIs) are transient or permanent connections between proteins, and they are important for many biological phenomena such as s...
Gene identification represents the first step to a better understanding of the physiological role of the underlying protein and disease pathways, which in turn serves as a starting point for developing therapeutic interventions. Familial hypercholesterolemia is a hereditary metabolic disorder characterized by high low-density lipoprotein cholesterol levels. Hypercholesterolemia is a quantitativ...
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