Cryptic evolution has been defined as adaptive evolutionary change being masked by concurrent environmental change. Empirical studies of cryptic evolution have usually invoked a changing climate and/or increasing population density as the form of detrimental environmental change experienced by a population undergoing cryptic evolution. However, Fisher (1958) emphasized that evolutionary change ...

We develop a dynamic structural model to examine the e¤ects of di¤ering beliefs of the manager and outsider investors regarding the pro…tability of a …rm’s projects and managershareholder agency con‡icts on its capital structure. The manager receives dynamic incentives through explicit contracts with shareholders whose implementation through …nancial securities leads to a dynamic capital struct...

Earlier studies have revealed age-dependent differences in perception by dynamic touch. In the present study, we examined whether the capacity to learn deteriorates with aging. Adopting an ecological approach to learning, the authors examined the process of attunement--that is, the changes in what informational variable is exploited. Young and elderly adults were trained to perceive the lengths...

To test if antipsychotic medication treatment of Parkinson's disease (PD) patients with mild hallucinations and retained insight delays deterioration to delusions or hallucinations without insight. We identified subjects at the time they developed their first hallucination, based on documented progression in their UPDRS thought disorder (TD) score from <2 to 2 ("benign" hallucinations with insi...

The 2014 Indian general election marked a single party – the Bharatiya Janata Party, winning a majority of seats in Lok Sabha, the first time since the 1984 election. The Congress, the other main national party, suffered its worst ever defeat. This election was termed by some as a 'critical election' signalling the advent of a new phase of a ‘BJP dominated’ party system in India. In this paper,...

The 2014 Indian general election marked a single party – the Bharatiya Janata Party, winning a majority of seats in Lok Sabha, the first time since the 1984 election. The Congress, the other main national party, suffered its worst ever defeat. This election was termed by some as a 'critical election' signalling the advent of a new phase of a ‘BJP dominated’ party system in India. In this paper,...

In this paper, we attempt to develop an inventory model for deteriorating items with the consideration of the fact that the use of preservation technology (PT) can reduce the deterioration rate significantly. In this model the shortages are allowed and salvage value is incorporated to the deteriorated items. Demand rate is constant, deterioration rate is time dependent with Weibull’s distributi...

Background/Aims. Subclinical atherosclerosis and long-term glycemic variability have been reported to predict incident chronic kidney disease (CKD) in the general population. However, these associations have not been investigated in patients with type 2 diabetes with preserved kidney function. Methods. We prospectively followed up 162 patients with type 2 diabetes (mean age, 62.3 years; 53.6% m...

Correlated survival times can be modelled by introducing a random effect, or frailty component, into the hazard function. For multivariate survival data we extend a non-PH model, the generalized time-dependent logistic survival model, to include random effects. The hierarchical-likelihood procedure, which obviates the need for marginalization over the random effect distribution, is derived for ...