Libman-Sacks endocarditis of the mitral valve was first described by Libman and Sacks in 1924. Currently, the sterile verrucous vegetative lesions seen in Libman-Sacks endocarditis are regarded as a cardiac manifestation of both systemic lupus erythematosus (SLE) and the antiphospholipid syndrome (APS). Although typically mild and asymptomatic, complications of Libman-Sacks endocarditis may inc...

Pyoderma gangrenosum, Acne, and Hidradenitis Suppurativa (PASH) is a rare inflammatory syndrome, the exact etiology pathogenesis of which remains unknown. PASH syndrome belongs to spectrum Interleukin-1 driven auto-inflammatory diseases.InPatientsdiagnosed with various ways treatment are available individual differences in efficacy. We reporta new case that highlights features this condition co...

Cardiovascular disease in Marfan's syndrome presenting in childhood affects the mitral valve more often than the aortic valve or the aorta, as in adults. Early evaluation of the cardiovascular system is necessary for any child in whom Marfan's syndrome is suspected.

OBJECTIVE To evaluate the cardiovascular findings and clinical follow-up of patients with Williams-Beuren syndrome. METHODS We studied 20 patients (11 males, mean age at diagnosis: 5.9 years old), assessed for cardiovascular abnormalities with electrocardiography and Doppler echocardiography. Fluorescence in situ hybridization (FISH) was used to confirm the diagnosis of the syndrome. RESULT...

A rare case of Marfan's syndrome presenting as an intrapartum death is described. Recognisable mitral valve lesions were present.

background: this study was undertaken to compare the outcome in patients with moderate to severe ischemic mitral regurgitation (imr) undergoing coronary artery bypass grafting (cabg) with either mitral valve repair or mitral valve replacement. methods: between march 2002 and february 2005, 49 consecutive patients (mean age: 62.84±8.42 years; mean euroscore: 10.03±3.12) with coronary artery dise...

severe inflammation after cardiopulmonary bypass with the vasculitis of the acral extremity and vertebro-basilar arterial system leads to the locked-in syndrome and blue toe syndrome. in broad terms, systemic, idiopathic, and environmental factors provoke syndromes that present with digital discoloration or the blue toe syndrome. painful digital discoloration, accompanied by ulceration, suggest...

OBJECTIVE The purpose of this study was to assess whether joint hypermobility syndrome is more frequent in patients with panic disorder, agoraphobia, or both than in control subjects and, if so, to determine whether mitral valve prolapse modifies or accounts in part for the association. METHOD A case-control study was conducted in a general teaching hospital outpatient clinic. Subjects were 9...

Barlow's syndrome has become a regular, often-used and very often misused diagnosis. Its description followed extensive, prolonged and detailed clinical observation by JB Barlow and his co-workers. This major research effort was necessary because of the protean manifestations of the condition. The differentiation of Barlow's syndrome from other conditions with similar and sometimes identical sy...

OBJECTIVE The Cox Maze procedure is widely performed for the surgical treatment of atrial fibrillation. However it requires numerous incision lines and therefore is a time-consuming operation. We report a simplified operation for chronic atrial fibrillation associated with mitral valve disease. METHODS Pulmonary vein isolation procedure was performed on atrial fibrillation associated with mit...