نتایج جستجو برای: prokinetic
تعداد نتایج: 499 فیلتر نتایج به سال:
Motilin receptors (provisional nomenclature) are activated by motilin, a 22 amino-acid peptide derived from precursor (MLN, P12872), which may also generate motilin-associated peptide. There significant species differences in the structure of motilin and its receptor, functions motilin. In humans large mammals such as dog, activation these released endocrine cells duodenal mucosa during fasting...
INTRODUCTION Domperidone is a dopamine receptor antagonist with peripheral prokinetic and central antiemetic properties. Prolongation of the QTc interval with chronic use of oral domperidone in standard doses has been reported in the literature. Our goal was to investigate cardiac toxicity in patients receiving 2-fold greater doses than in previous reports. METHODS A retrospective chart revie...
BACKGROUND A substantial proportion of patients with gastro-oesophageal reflux disease (GERD) have only a partial response to proton pump inhibitor (PPI) therapy. Prokinetic drugs may improve reflux symptoms by enhancing oesophageal motility and gastric emptying. AIM To evaluate the effect of revexepride, a novel prokinetic 5-hydroxytryptamine type 4 (5-HT4 ) receptor agonist, compared with p...
BACKGROUND Chronic idiopathic intestinal pseudo-obstruction, a syndrome of ineffectual motility due to a primary disorder of enteric nerve or muscle, is rare. AIMS To determine the clinical spectrum, underlying pathologies, response to treatments, and prognosis in a consecutive unselected group of patients. METHODS Cross sectional study of all patients with clinical and radiological feature...
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