Muscular dystrophy refers to a group of genetic diseases associated with progressive muscle weakness and atrophy. Duchenne Muscular Dystrophy (DMD) is a particularly severe and fatal form of this disease, affecting 1 in 3500 live born males [1]. It is caused by mutations in the dystrophin gene leading to a loss of dystrophin [2]. This results in progressive muscle degeneration, wheelchair depen...

INTRODUCTION Fibromyalgia (FM) is characterized by persistent widespread pain, increased pain sensitivity and tenderness. Muscle strength in women with FM is reduced compared to healthy women. The aim of this study was to examine the effects of a progressive resistance exercise program on muscle strength, health status, and current pain intensity in women with FM. METHODS A total of 130 women...

In order to study oxygen consumption (VO2) for a given work load at the exhaustive level of a graded cycling exercise in well-trained runners, a progressive cycle ergometer exercise test was performed on 9 sprinters and 12 endurance runners, all in good national standing; 12 sedentary men served as control subjects. The relationship between VO2 and work-output appeared to be linear in most of t...

In order to study oxygen consumption (VO2) for a given work load at the exhaustive level of a graded cycling exercise in well-trained runners, a progressive cycle ergometer exercise test was performed on 9 sprinters and 12 endurance runners, all in good national standing; 12 sedentary men served as control subjects. The relationship between V02 and work-output appeared to be linear in most of t...

Despite improved prognosis for patients with cystic fibrosis (CF), they continue to suffer from progressive decline in pulmonary function and exercise tolerance. Beyond puberty, female patients have greater loss of pulmonary function and higher mortality than males, yet no one has studied male-female differences in exercise tolerance among patients. We therefore compared the responses to progre...

This study evaluated whether inspiratory muscle training (IMT) could increase inspiratory muscle strength and endurance and exercise performance in 11 patients with cystic fibrosis (CF) with moderately severe airflow limitation. The IMT consisted of breathing through an inspiratory resistance (IR) for 15 min twice daily for 4 wk, preceded or followed by a 4-wk control period. After IMT, there w...

BACKGROUND Interventions including physical exercise may help improve the outcomes of late-life major depression, but few studies are available. AIMS To investigate whether augmenting sertraline therapy with physical exercise leads to better outcomes of late-life major depression. METHOD Primary care patients (465 years) with major depression were randomised to 24 weeks of higher-intensity,...

Aims: Active and progressive resistance training has a key role in functional recovery and quality of life in patients with MS. Therefore, this study aimed to investigate the effects of isotonic and isometric exercises on balance and ability in patients with MS. Materials & Methods: In this randomized clinical trial, 60 patients with MS admitted to MS Special Diseases Center in Yasuj during 20...

OBJECTIVE To determine if a programme of progressive resistance exercise, mobilisation and orientation, in addition to usual care, was superior to usual care alone in the prevention of incident delirium in older hospitalised patients. DESIGN A randomised controlled trial. SETTING The study was performed at a secondary referral hospital in Melbourne, Australia between May 2005 and December 2...