نتایج جستجو برای: progesterone receptors
تعداد نتایج: 241696 فیلتر نتایج به سال:
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The role of sex hormones in the pathogenesis of lung cancer is still unknown. There are conflicting results regarding immunohistochemical detection of the estrogen and progesterone receptors expression in non small cell lung cancer. To clarify these discrepancies 32 samples of lung carcinoma tissues obtained by lobectomy or pneumonectomy were studied. Two monoclonal antibodies (6F11 and ID5) fo...
The involvement of the arachidonic acid (AA) products, noradrenaline (NA) and LH in the stimulatory effect of progesterone on its own synthesis was tested using slices of CL from days 5-10 of the oestrous cycle of cow. Slices of CL (45-50 mg) were pre-incubated for 24 h, then the medium was replaced with fresh medium and 45 min later was supplemented with LH (100 ng/ml) as a positive control, o...
BACKGROUND Progesterone levels are higher in placental barriers during pregnancy, but the effect of progesterone on human immunodeficiency virus type 1 (HIV-1) infection in placental cells has not been addressed. We hypothesize that progesterone may affect HIV infection. METHODS Purified trophoblastic cells and trophoblastic cell lines were infected or transfected with HIV-1, and the effect o...
Rat cerebellar granule cells were cultured for 5 days with progesterone, resulting in the conversion of progesterone to allopregnanolone, a potent and efficacious modulator of gamma-aminobutyric acid (GABA) type-A receptors, as well as in decreases in the abundance of GABA(A) receptor alpha(1), alpha(3), alpha(5), and gamma(2) subunit mRNAs. These effects were accompanied by decreases in the ef...
Estradici and progesterone receptor concentrations were determined in cytoplasmic and nuclear fractions of endometrial cancer specimens taken from 43 postmenopausal women. In addition to receptors, ornithine decarboxylase and 17/?-estradiol hydroxysteroid dehydrogenase activities were also meas ured before and after antiestrogen treatment to evaluate hor mone sensitivity of the tumors. Fifteen ...
This short-term study of the relative importance of estrogen and progesterone receptors shows that progesterone receptor correlates better than estrogen receptor with tumor recurrence regardless of lymph-node status. Life-table analysis has effectively identified only two groups of patients that may be classified by progesterone receptor status alone. Progesterone-receptor negativity correlated...
background: triple negative breast cancer (tnbc) is reported to be associated with a high risk of recurrence, poor overall survival (os), and disease-free survival (dfs) rates. this study evaluated the clincopathological features and survival of non-metastatic tnbc women in the capital of iran compared with other areas of the world. methods: in a retrospective study, 119 women with tnbc based o...
CONTEXT Diagnostic staging is an important prognostic factor for endometrial adenocarcinoma. Apart from the histological type and histological grade, some markers seem to be associated with the stage and biological behavior of the disease. Among these are p53, estrogen and progesterone receptors. OBJECTIVE The objectives of the present study were: to compare histological type and grading of e...
Taenia solium cysticercosis is a health problem in underdeveloped and developed countries. Sex hormones are involved in cysticercosis prevalence in female and male pigs. Here, we evaluated the effects of progesterone and its antagonist RU486 on scolex evagination, which is the initial step in the development of the adult worm. Interestingly, progesterone increased T. solium scolex evagination a...
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