Surfactant protein C (SP-C), a 3.7-kDa hydrophobic lung-specific protein, is synthesized and secreted by pulmonary type II cells through proteolytic processing of a 21-kDa propeptide (SP-C21) by currently undefined pathways. Previously, we reported the production of a polyclonal antibody against rat SP-C21 (anti-CPROSP-C) using a synthetic peptide as the immunizing antigen (Beers, M. F., Wali, ...

The nucleus in eukaryotic cells is a highly organized and dynamic structure containing numerous subnuclear bodies. The morphological appearance of nuclear bodies seems to be a reflection of ongoing functions, such as DNA replication, transcription, repair, RNA processing and RNA transport. The integrator complex mediates processing of small nuclear RNA (snRNA), so it might play a role in nuclea...

In the human brain information about bodies and faces is processed in specialized cortical regions named EBA and FBA (extrastriate and fusiform body area) and OFA and FFA (occipital and fusiform face area), respectively. Here we investigate with functional magnetic resonance imaging (fMRI) the cortical areas responsible for the identification of individual bodies and the distinction between 'se...

Interactive bodies collision detection and elimination is one of the most popular task nowadays. Collisions can be detected in different ways. Collision search using space voxelization is one of the most fast. This paper describes improved voxel model that covers only area of collision interest and quickly eliminates collisions. This new method can be useful in real time collision processing of...

We derive explicit Lorentz-invariant solution of the Einstein and null geodesic equations for data processing of the time delay and ranging experiments in gravitational field of moving gravitating bodies of the solar system the Sun and major planets. We discuss generalrelativistic interpretation of these experiments and the limitations imposed by motion of the massive bodies on measurement of t...

New clues to the function of the Cajal body Small RNA molecules play major roles in a number of cellular functions. Depending on their predominant cellular location, small RNAs have been classified as nuclear (sn), nucleolar (sno) or cytoplasmic (sc). The nucleoplasmic species include the spliceosomal snRNAs (U1, U2, U4, U5 and U6) and the U7 snRNA required for histone pre-mRNA 3′-end formation...

Kern, W.. Learning convex bodies under uniform distribution. Information Processing Letters 43 (lY92) 35-3’). We prove that the class of convex bodies contained in a fixed (prescribed) bounded region R c lQd is PAC-learnable, if the positive examples are drawn according to the uniform distribution Df on the target concept (the distribution Dm on the negative examples may be arbitrary). Our resu...

Processing bodies (P-bodies) are dynamic cytoplasmic structures involved in mRNA degradation, but the mechanism that governs their formation is poorly understood. In this paper, we address a role of Like-Sm (LSm) proteins in formation of P-bodies and provide evidence that depletion of nuclear LSm8 increases the number of P-bodies, while LSm8 overexpression leads to P-body loss. We show that LSm...

The promyelocytic leukemia (PML) protein has been implicated in many cellular pathways, but it is unclear whether the accumulation of PML and other proteins into PML nuclear bodies is a regulated or random process. In this paper we have used a variety of physiological stresses, including heat stress, Cd+2 exposure and adenovirus E1A expression, as tools to study the principles underlying the as...